10-K Filing

Q32 Bio Inc. CIK: 1661998 FY 2021

Filing Information

Form Type	10-K
Accession Number	`0000950170-22-004401`
Period End Date	20211231
Filing Date	20220323
Fiscal Year	2021
Fiscal Period	FY
XBRL Instance	fixx-20211231_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 67 Income Statement 20 Cash Flow Statement 60 Stockholders Equity 18 Comprehensive Income 8

Balance Sheet 67 line items

Line Item	Tag	Value	Unit	Period
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$108.38M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$217.43M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Short-term investments	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$47.49M	USD	Point-in-time
Short-term investments	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	-	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Assets Held For Sale	`AssetsHeldForSaleNotPartOfDisposalGroup`	-	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Assets Held For Sale	`AssetsHeldForSaleNotPartOfDisposalGroup`	$28.91M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	200.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	200.00M	shares	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$2.13M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$7.13M	USD	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	57.15M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	50.27M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$219.56M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$191.91M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	50.27M	shares	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	57.15M	shares	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$2.25M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$37.00M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$6.83M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$5.90M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$15.61M	USD	Point-in-time
Restricted cash	`RestrictedCash`	$1.95M	USD	Point-in-time
Restricted cash	`RestrictedCash`	$1.27M	USD	Point-in-time
Total assets	`Assets`	$211.72M	USD	Point-in-time
Total assets	`Assets`	$263.74M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$2.37M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$4.72M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedExpensesAndOtherLiabilitiesCurrent`	$9.80M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedExpensesAndOtherLiabilitiesCurrent`	$11.41M	USD	Point-in-time
Operating Lease Liabilities	`OperatingLeaseLiabilityCurrent`	$15.44M	USD	Point-in-time
Operating Lease Liabilities	`OperatingLeaseLiabilityCurrent`	$2.50M	USD	Point-in-time
Operating Lease Liabilities	`OperatingLeaseLiabilityCurrent`	$246.00K	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$5.63M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$3.21M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$17.23M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$22.66M	USD	Point-in-time
Operating lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$23.69M	USD	Point-in-time
Operating lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$12.94M	USD	Point-in-time
Deferred revenue, net of current portion	`ContractWithCustomerLiabilityNoncurrent`	$1.16M	USD	Point-in-time
Deferred revenue, net of current portion	`ContractWithCustomerLiabilityNoncurrent`	$32.14M	USD	Point-in-time
Total liabilities	`Liabilities`	$42.07M	USD	Point-in-time
Total liabilities	`Liabilities`	$67.74M	USD	Point-in-time
Preferred stock, $0.0001 par value, 10,000,000 shares authorized as of December 31, 2021 and 2020; no shares issued and outstanding at December 31, 2021 and 2020	`PreferredStockValue`	-	USD	Point-in-time
Preferred stock, $0.0001 par value, 10,000,000 shares authorized as of December 31, 2021 and 2020; no shares issued and outstanding at December 31, 2021 and 2020	`PreferredStockValue`	-	USD	Point-in-time
Common stock, $0.0001 par value; 200,000,000 shares authorized as of December 31, 2021 and 2020; 57,150,274 and 50,268,666 shares issued as of December 31, 2021 and 2020, respectively; and 57,150,274 and 50,265,575 shares outstanding as of December 31, 2021and 2020, respectively	`CommonStockValue`	$6.00K	USD	Point-in-time
Common stock, $0.0001 par value; 200,000,000 shares authorized as of December 31, 2021 and 2020; 57,150,274 and 50,268,666 shares issued as of December 31, 2021 and 2020, respectively; and 57,150,274 and 50,265,575 shares outstanding as of December 31, 2021and 2020, respectively	`CommonStockValue`	$5.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$524.36M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$593.78M	USD	Point-in-time
Accumulated other comprehensive gain	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-7.00K	USD	Point-in-time
Accumulated other comprehensive gain	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	-	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-424.13M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-328.37M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$196.00M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$169.65M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$258.51M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$263.74M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$211.72M	USD	Point-in-time

Income Statement 20 line items

Line Item	Tag	Value	Unit	Period
Collaboration revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$2.70M	USD	Annual
Collaboration revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$33.97M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$100.39M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$93.08M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$32.57M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$36.84M	USD	Annual
Total operating expenses	`OperatingExpenses`	$129.92M	USD	Annual
Total operating expenses	`OperatingExpenses`	$132.97M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-95.95M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-130.26M	USD	Annual
Interest income	`InvestmentIncomeNonoperating`	$185.00K	USD	Annual
Interest income	`InvestmentIncomeNonoperating`	$1.57M	USD	Annual
Total other income	`OtherNonoperatingIncomeExpense`	$185.00K	USD	Annual
Total other income	`OtherNonoperatingIncomeExpense`	$1.57M	USD	Annual
Net loss	`NetIncomeLoss`	$-128.69M	USD	Annual
Net loss	`NetIncomeLoss`	$-95.76M	USD	Annual
Net loss per share-basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.73	USD	Annual
Net loss per share-basic and diluted	`EarningsPerShareBasicAndDiluted`	$-2.80	USD	Annual
Weighted average common shares outstanding-basic and diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	45.91M	shares	Annual
Weighted average common shares outstanding-basic and diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	55.28M	shares	Annual

Cash Flow Statement 60 line items

Line Item	Tag	Value	Unit	Period
Net loss	`ProfitLoss`	$-95.76M	USD	Annual
Net loss	`ProfitLoss`	$-128.69M	USD	Annual
Depreciation	`Depreciation`	$7.96M	USD	Annual
Depreciation	`Depreciation`	$8.35M	USD	Annual
Noncash lease expense	`NonCashLeaseExpense`	$939.00K	USD	Annual
Noncash lease expense	`NonCashLeaseExpense`	$1.19M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$17.25M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$13.25M	USD	Annual
Amortization of premium (accretion of discount) on short-term investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$198.00K	USD	Annual
Amortization of premium (accretion of discount) on short-term investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-894.00K	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-888.00K	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-133.00K	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$5.00M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-2.06M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$2.46M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-2.49M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$1.50M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$2.43M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$6.82M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-33.41M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-2.25M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-2.41M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-94.33M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-109.75M	USD	Annual
Purchases of short-term investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$97.39M	USD	Annual
Purchases of short-term investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$19.99M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleOfAvailableForSaleSecuritiesDebt`	$228.62M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleOfAvailableForSaleSecuritiesDebt`	$49.00M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$3.73M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$2.40M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$204.90M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-50.79M	USD	Annual
Proceeds from issuance of common stock in follow-on public offering, net of discounts and issuance costs	`ProceedsFromIssuanceOfCommonStock`	-	USD	Annual
Proceeds from issuance of common stock in follow-on public offering, net of discounts and issuance costs	`ProceedsFromIssuanceOfCommonStock`	$49.74M	USD	Annual
Proceeds From Issuance Of Common Stock Pursuant To ATM Financing Net Of Discounts And Issuance Costs	`ProceedsFromIssuanceOfCommonStockPursuantToAtmFinancingNetOfDiscountsAndIssuanceCosts`	$1.45M	USD	Annual
Proceeds From Issuance Of Common Stock Pursuant To ATM Financing Net Of Discounts And Issuance Costs	`ProceedsFromIssuanceOfCommonStockPursuantToAtmFinancingNetOfDiscountsAndIssuanceCosts`	-	USD	Annual
Proceeds from issuance of common stock in private placement	`ProceedsFromIssuanceOfPrivatePlacement`	-	USD	Annual
Proceeds from issuance of common stock in private placement	`ProceedsFromIssuanceOfPrivatePlacement`	$51.98M	USD	Annual
Proceeds from issuance of common stock from option exercises	`ProceedsFromStockOptionsExercised`	$176.00K	USD	Annual
Proceeds from issuance of common stock from option exercises	`ProceedsFromStockOptionsExercised`	$145.00K	USD	Annual
Proceeds from issuance of common stock pursuant to employee stock purchase plan	`ProceedsFromStockPlans`	$938.00K	USD	Annual
Proceeds from issuance of common stock pursuant to employee stock purchase plan	`ProceedsFromStockPlans`	$826.00K	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$53.09M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$52.17M	USD	Annual
Net change in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$163.66M	USD	Annual
Net change in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-108.37M	USD	Annual
Cash, cash equivalents and restricted cash, beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$55.05M	USD	Point-in-time
Cash, cash equivalents and restricted cash, beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$218.71M	USD	Point-in-time
Cash, cash equivalents and restricted cash, beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$110.33M	USD	Point-in-time
Cash, cash equivalents and restricted cash, end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$55.05M	USD	Point-in-time
Cash, cash equivalents and restricted cash, end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$218.71M	USD	Point-in-time
Cash, cash equivalents and restricted cash, end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$110.33M	USD	Point-in-time
Reclassification of liability for common stock vested	`ReclassificationOfLiabilityForCommonStockVestedInNoncashTransactions`	$13.00K	USD	Annual
Reclassification of liability for common stock vested	`ReclassificationOfLiabilityForCommonStockVestedInNoncashTransactions`	$24.00K	USD	Annual
Property and equipment additions included in accounts payable	`CapitalExpendituresIncurredButNotYetPaid`	$110.00K	USD	Annual
Property and equipment additions included in accounts payable	`CapitalExpendituresIncurredButNotYetPaid`	$241.00K	USD	Annual
Property and equipment additions included in accrued expenses and other liabilities	`PropertyAndEquipmentAdditionsIncludedInAccruedExpensesAndOtherLiabilities`	$116.00K	USD	Annual
Property and equipment additions included in accrued expenses and other liabilities	`PropertyAndEquipmentAdditionsIncludedInAccruedExpensesAndOtherLiabilities`	-	USD	Annual
Unrealized (loss) gain on available for sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-7.00K	USD	Annual
Unrealized (loss) gain on available for sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-183.00K	USD	Annual

Stockholders Equity 18 line items

Line Item	Tag	Value	Unit	Period
Beginning balance	`StockholdersEquity`	$196.00M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$169.65M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$258.51M	USD	Point-in-time
Vesting of common stock from option exercises	`StockIssuedDuringPeriodValueVestingOfCommonStockFromOptionExercise`	$13.00K	USD	Annual
Vesting of common stock from option exercises	`StockIssuedDuringPeriodValueVestingOfCommonStockFromOptionExercise`	$24.00K	USD	Annual
Issuance of common stock from option exercises	`StockIssuedDuringPeriodValueStockOptionsExercised`	$176.00K	USD	Annual
Issuance of common stock from option exercises	`StockIssuedDuringPeriodValueStockOptionsExercised`	$145.00K	USD	Annual
Issuance of common stock pursuant to employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$826.00K	USD	Annual
Issuance of common stock pursuant to employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$938.00K	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition`	$13.25M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationStockOptionsRequisiteServicePeriodRecognition`	$17.25M	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent`	$-7.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent`	$-183.00K	USD	Annual
Net loss	`NetIncomeLoss`	$-128.69M	USD	Annual
Net loss	`NetIncomeLoss`	$-95.76M	USD	Annual
Ending balance	`StockholdersEquity`	$169.65M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$196.00M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$258.51M	USD	Point-in-time

Comprehensive Income 8 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-128.69M	USD	Annual
Net loss	`NetIncomeLoss`	$-95.76M	USD	Annual
Change in unrealized gain (loss) on available for sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-7.00K	USD	Annual
Change in unrealized gain (loss) on available for sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-183.00K	USD	Annual
Total other comprehensive gain (loss)	`OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent`	$-7.00K	USD	Annual
Total other comprehensive gain (loss)	`OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent`	$-183.00K	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-128.88M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-95.77M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.