10-Q Filing

REGENXBIO Inc. CIK: 1590877 Q3 2022

Filing Information

Form Type	10-Q
Accession Number	`0000950170-22-021567`
Period End Date	20220930
Filing Date	20221103
Fiscal Year	2022
Fiscal Period	Q3
XBRL Instance	rgnx-20220930_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 82 Income Statement 82 Cash Flow Statement 73 Stockholders Equity 34

Balance Sheet 82 line items

Line Item	Tag	Value	Unit	Period
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$345.21M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$228.39M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$118.54M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$263.87M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$112.23M	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$32.55M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$32.44M	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$14.82M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$18.75M	USD	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	43.29M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	42.83M	shares	Point-in-time
Other current assets	`OtherAssetsCurrent`	$6.85M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$10.20M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	43.29M	shares	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	42.83M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$436.64M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$518.83M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesNoncurrent`	$234.59M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesNoncurrent`	$391.91M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetNoncurrent`	$2.26M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetNoncurrent`	$1.80M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$140.91M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$131.55M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$60.90M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$59.47M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$1.33M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$2.03M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$2.03M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$8.35M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$6.43M	USD	Point-in-time
Total assets	`Assets`	$1.11B	USD	Point-in-time
Total assets	`Assets`	$883.79M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$11.39M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$25.21M	USD	Point-in-time
Accrued expenses and other current liabilities	`AccruedExpensesAndOtherCurrentLiabilities`	$44.46M	USD	Point-in-time
Accrued expenses and other current liabilities	`AccruedExpensesAndOtherCurrentLiabilities`	$76.11M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$5.90M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$3.33M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$1.75M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$3.61M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesCurrent`	$44.37M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesCurrent`	$37.89M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$130.47M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$123.55M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$84.93M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$84.67M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesNonCurrent`	$133.46M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesNonCurrent`	$103.08M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$745.00K	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$8.66M	USD	Point-in-time
Total liabilities	`Liabilities`	$349.61M	USD	Point-in-time
Total liabilities	`Liabilities`	$319.97M	USD	Point-in-time
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at September 30, 2022 and December 31, 2021	`PreferredStockValue`	-	USD	Point-in-time
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at September 30, 2022 and December 31, 2021	`PreferredStockValue`	-	USD	Point-in-time
Common stock; $0.0001 par value; 100,000 shares authorized at September 30, 2022 and December 31, 2021; 43,292 and 42,831 shares issued and outstanding at September 30, 2022 and December 31, 2021, respectively	`CommonStockValue`	$4.00K	USD	Point-in-time
Common stock; $0.0001 par value; 100,000 shares authorized at September 30, 2022 and December 31, 2021; 43,292 and 42,831 shares issued and outstanding at September 30, 2022 and December 31, 2021, respectively	`CommonStockValue`	$4.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$928.10M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$963.69M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-2.57M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-18.26M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-161.23M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-381.62M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$461.41M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$507.25M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$377.75M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$563.82M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$764.30M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$630.52M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$883.79M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$1.11B	USD	Point-in-time

Income Statement 82 line items

Line Item	Tag	Value	Unit	Period
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$71.69M	USD	3 Qtrs
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$26.51M	USD	1 Quarter
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$81.38M	USD	3 Qtrs
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$30.77M	USD	1 Quarter
Cost of revenues	`CostOfGoodsAndServicesSold`	$28.77M	USD	3 Qtrs
Cost of revenues	`CostOfGoodsAndServicesSold`	$41.76M	USD	3 Qtrs
Cost of revenues	`CostOfGoodsAndServicesSold`	$14.11M	USD	1 Quarter
Cost of revenues	`CostOfGoodsAndServicesSold`	$13.09M	USD	1 Quarter
Research and development	`ResearchAndDevelopmentExpense`	$47.85M	USD	1 Quarter
Research and development	`ResearchAndDevelopmentExpense`	$63.31M	USD	1 Quarter
Research and development	`ResearchAndDevelopmentExpense`	$133.46M	USD	3 Qtrs
Research and development	`ResearchAndDevelopmentExpense`	$179.95M	USD	3 Qtrs
General and administrative	`GeneralAndAdministrativeExpense`	$21.03M	USD	1 Quarter
General and administrative	`GeneralAndAdministrativeExpense`	$57.29M	USD	3 Qtrs
General and administrative	`GeneralAndAdministrativeExpense`	$20.92M	USD	1 Quarter
General and administrative	`GeneralAndAdministrativeExpense`	$64.07M	USD	3 Qtrs
Credit losses and other	`CreditLossesAndOther`	$229.00K	USD	1 Quarter
Credit losses and other	`CreditLossesAndOther`	$5.78M	USD	3 Qtrs
Credit losses and other	`CreditLossesAndOther`	$5.13M	USD	1 Quarter
Credit losses and other	`CreditLossesAndOther`	$703.00K	USD	3 Qtrs
Total operating expenses	`CostsAndExpenses`	$88.12M	USD	1 Quarter
Total operating expenses	`CostsAndExpenses`	$97.56M	USD	1 Quarter
Total operating expenses	`CostsAndExpenses`	$286.48M	USD	3 Qtrs
Total operating expenses	`CostsAndExpenses`	$225.31M	USD	3 Qtrs
Loss from operations	`OperatingIncomeLoss`	$-205.10M	USD	3 Qtrs
Loss from operations	`OperatingIncomeLoss`	$-153.62M	USD	3 Qtrs
Loss from operations	`OperatingIncomeLoss`	$-57.35M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-71.05M	USD	1 Quarter
Interest income from licensing	`InterestIncomeFromLicencing`	$117.00K	USD	1 Quarter
Interest income from licensing	`InterestIncomeFromLicencing`	$700.00K	USD	3 Qtrs
Interest income from licensing	`InterestIncomeFromLicencing`	$18.00K	USD	1 Quarter
Interest income from licensing	`InterestIncomeFromLicencing`	$265.00K	USD	3 Qtrs
Investment income	`InvestmentIncomeNet`	$5.54M	USD	1 Quarter
Investment income	`InvestmentIncomeNet`	$6.51M	USD	3 Qtrs
Investment income	`InvestmentIncomeNet`	$1.50M	USD	1 Quarter
Investment income	`InvestmentIncomeNet`	$3.36M	USD	3 Qtrs
Interest expense	`InterestExpense`	$6.71M	USD	1 Quarter
Interest expense	`InterestExpense`	$19.78M	USD	3 Qtrs
Interest expense	`InterestExpense`	$18.94M	USD	3 Qtrs
Interest expense	`InterestExpense`	$5.95M	USD	1 Quarter
Total other income (expense)	`NonoperatingIncomeExpense`	$-15.32M	USD	3 Qtrs
Total other income (expense)	`NonoperatingIncomeExpense`	$-1.06M	USD	1 Quarter
Total other income (expense)	`NonoperatingIncomeExpense`	$-4.44M	USD	1 Quarter
Total other income (expense)	`NonoperatingIncomeExpense`	$-12.56M	USD	3 Qtrs
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-58.41M	USD	1 Quarter
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-75.48M	USD	1 Quarter
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-220.43M	USD	3 Qtrs
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-166.18M	USD	3 Qtrs
Income Tax Benefit (Expense)	`IncomeTaxExpenseBenefit`	$-41.00K	USD	3 Qtrs
Income Tax Benefit (Expense)	`IncomeTaxExpenseBenefit`	$4.00K	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-166.18M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-220.39M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-58.41M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-75.48M	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-15.69M	USD	3 Qtrs
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-30.00K	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-3.49M	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-925.00K	USD	3 Qtrs
Total other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-925.00K	USD	3 Qtrs
Total other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-3.49M	USD	1 Quarter
Total other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-30.00K	USD	1 Quarter
Total other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-15.69M	USD	3 Qtrs
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-78.98M	USD	1 Quarter
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-58.44M	USD	1 Quarter
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-236.07M	USD	3 Qtrs
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-167.11M	USD	3 Qtrs
Net loss per share, basic	`EarningsPerShareBasic`	$-3.93	USD	3 Qtrs
Net loss per share, basic	`EarningsPerShareBasic`	$-1.75	USD	1 Quarter
Net loss per share, basic	`EarningsPerShareBasic`	$-1.37	USD	1 Quarter
Net loss per share, basic	`EarningsPerShareBasic`	$-5.11	USD	3 Qtrs
Net loss per share, diluted	`EarningsPerShareDiluted`	$-3.93	USD	3 Qtrs
Net loss per share, diluted	`EarningsPerShareDiluted`	$-1.37	USD	1 Quarter
Net loss per share, diluted	`EarningsPerShareDiluted`	$-1.75	USD	1 Quarter
Net loss per share, diluted	`EarningsPerShareDiluted`	$-5.11	USD	3 Qtrs
Weighted-average common shares outstanding, basic	`WeightedAverageNumberOfSharesOutstandingBasic`	43,103.00	shares	3 Qtrs
Weighted-average common shares outstanding, basic	`WeightedAverageNumberOfSharesOutstandingBasic`	42,629.00	shares	1 Quarter
Weighted-average common shares outstanding, basic	`WeightedAverageNumberOfSharesOutstandingBasic`	43,251.00	shares	1 Quarter
Weighted-average common shares outstanding, basic	`WeightedAverageNumberOfSharesOutstandingBasic`	42,324.00	shares	3 Qtrs
Weighted-average common shares outstanding, diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	42,324.00	shares	3 Qtrs
Weighted-average common shares outstanding, diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	42,629.00	shares	1 Quarter
Weighted-average common shares outstanding, diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	43,103.00	shares	3 Qtrs
Weighted-average common shares outstanding, diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	43,251.00	shares	1 Quarter

Cash Flow Statement 73 line items

Line Item	Tag	Value	Unit	Period
Net loss	`ProfitLoss`	$-220.39M	USD	3 Qtrs
Net loss	`ProfitLoss`	$-166.18M	USD	3 Qtrs
Stock-based compensation expense	`ShareBasedCompensation`	$29.65M	USD	3 Qtrs
Stock-based compensation expense	`ShareBasedCompensation`	$31.38M	USD	3 Qtrs
Depreciation and amortization	`DepreciationAndAmortization`	$6.96M	USD	3 Qtrs
Depreciation and amortization	`DepreciationAndAmortization`	$8.78M	USD	3 Qtrs
Provision for credit losses	`ProvisionForOtherCreditLosses`	$5.00M	USD	1 Quarter
Provision for credit losses	`ProvisionForOtherCreditLosses`	$5.53M	USD	3 Qtrs
Provision for credit losses	`ProvisionForOtherCreditLosses`	-	USD	1 Quarter
Provision for credit losses	`ProvisionForOtherCreditLosses`	-	USD	3 Qtrs
Net amortization of premiums on marketable debt securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-4.38M	USD	3 Qtrs
Net amortization of premiums on marketable debt securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-3.81M	USD	3 Qtrs
Net loss (gain) on investments	`GainLossOnInvestments`	$-79.00K	USD	3 Qtrs
Net loss (gain) on investments	`GainLossOnInvestments`	$5.19M	USD	3 Qtrs
Imputed interest income from licensing	`ImputedInterestIncomeFromLicensing`	$264.00K	USD	3 Qtrs
Imputed interest income from licensing	`ImputedInterestIncomeFromLicensing`	$341.00K	USD	3 Qtrs
Non-cash interest expense	`NonCashInterestExpense`	$767.00K	USD	3 Qtrs
Non-cash interest expense	`NonCashInterestExpense`	$4.52M	USD	3 Qtrs
Other non-cash adjustments	`OtherNoncashIncomeExpense`	$51.00K	USD	3 Qtrs
Other non-cash adjustments	`OtherNoncashIncomeExpense`	$-540.00K	USD	3 Qtrs
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$7.89M	USD	3 Qtrs
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$22.00K	USD	3 Qtrs
Prepaid expenses	`IncreaseDecreaseInPrepaidExpense`	$-3.93M	USD	3 Qtrs
Prepaid expenses	`IncreaseDecreaseInPrepaidExpense`	$7.90M	USD	3 Qtrs
Other current assets	`IncreaseDecreaseInOtherCurrentAssets`	$3.31M	USD	3 Qtrs
Other current assets	`IncreaseDecreaseInOtherCurrentAssets`	$-2.75M	USD	3 Qtrs
Operating lease right-of-use assets	`IncreaseDecreaseInOperatingLeaseRightOfUseAssets`	$-3.08M	USD	3 Qtrs
Operating lease right-of-use assets	`IncreaseDecreaseInOperatingLeaseRightOfUseAssets`	$-3.78M	USD	3 Qtrs
Other assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$1.92M	USD	3 Qtrs
Other assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$4.40M	USD	3 Qtrs
Accounts payable	`IncreaseDecreaseInAccountsPayableTrade`	$16.88M	USD	3 Qtrs
Accounts payable	`IncreaseDecreaseInAccountsPayableTrade`	$6.50M	USD	3 Qtrs
Accrued expenses and other current liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$473.00K	USD	3 Qtrs
Accrued expenses and other current liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$-28.24M	USD	3 Qtrs
Deferred revenue	`IncreaseDecreaseInDeferredRevenue`	$2.82M	USD	3 Qtrs
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$10.85M	USD	3 Qtrs
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-50.00K	USD	3 Qtrs
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-2.00K	USD	3 Qtrs
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$7.94M	USD	3 Qtrs
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-168.12M	USD	3 Qtrs
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-122.62M	USD	3 Qtrs
Purchases of marketable debt securities	`PaymentsToAcquireMarketableSecurities`	$262.67M	USD	3 Qtrs
Purchases of marketable debt securities	`PaymentsToAcquireMarketableSecurities`	$172.91M	USD	3 Qtrs
Maturities of marketable debt securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$159.01M	USD	3 Qtrs
Maturities of marketable debt securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$136.39M	USD	3 Qtrs
Sales of equity securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$524.00K	USD	3 Qtrs
Sales of equity securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$5.56M	USD	3 Qtrs
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$25.25M	USD	3 Qtrs
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$69.56M	USD	3 Qtrs
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-190.28M	USD	3 Qtrs
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-38.63M	USD	3 Qtrs
Proceeds from exercise of stock options	`ProceedsFromStockOptionsExercised`	$3.30M	USD	3 Qtrs
Proceeds from exercise of stock options	`ProceedsFromStockOptionsExercised`	$2.76M	USD	3 Qtrs
Taxes paid related to net settlement of stock-based awards	`TaxesPaidRelatedToNetSettlementOfStockBasedAwards`	$284.00K	USD	3 Qtrs
Proceeds from issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans`	$1.74M	USD	3 Qtrs
Proceeds from issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans`	$1.77M	USD	3 Qtrs
Proceeds from public offering of common stock, net of underwriting discounts and commissions	`ProceedsFromIssuancesOfCommonStockNetOfUnderwritingDiscountsAndCommissions`	$216.44M	USD	3 Qtrs
Issuance costs for public offering of common stock	`PaymentsOfStockIssuanceCosts`	$379.00K	USD	3 Qtrs
Repayments under liability related to sale of future royalties, net of imputed interest	`RepaymentsUnderLiabilityRelatedToSaleOfFutureRoyalties`	$17.99M	USD	3 Qtrs
Repayments under liability related to sale of future royalties, net of imputed interest	`RepaymentsUnderLiabilityRelatedToSaleOfFutureRoyalties`	$24.14M	USD	3 Qtrs
Transaction costs for sale of future royalties	`PaymentsOfTransactionCostsForSaleOfFutureLoyalties`	$265.00K	USD	3 Qtrs
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$202.87M	USD	3 Qtrs
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-19.92M	USD	3 Qtrs
Net decrease in cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-226.66M	USD	3 Qtrs
Net decrease in cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-110.04M	USD	3 Qtrs
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$339.76M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$347.24M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$120.57M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$229.72M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$347.24M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$120.57M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$339.76M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$229.72M	USD	Point-in-time

Stockholders Equity 34 line items

Line Item	Tag	Value	Unit	Period
Balances	`StockholdersEquity`	$461.41M	USD	Point-in-time
Balances	`StockholdersEquity`	$507.25M	USD	Point-in-time
Balances	`StockholdersEquity`	$377.75M	USD	Point-in-time
Balances	`StockholdersEquity`	$563.82M	USD	Point-in-time
Balances	`StockholdersEquity`	$764.30M	USD	Point-in-time
Balances	`StockholdersEquity`	$630.52M	USD	Point-in-time
Issuance of common stock upon public offering, net of transaction costs	`StockIssuedDuringPeriodValueNewIssues`	$216.06M	USD	3 Qtrs
Vesting of restricted stock units, net of tax	`VestingOfRestrictedStockUnits`	$-284.00K	USD	3 Qtrs
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$1.73M	USD	1 Quarter
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.76M	USD	3 Qtrs
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$917.00K	USD	1 Quarter
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.30M	USD	3 Qtrs
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.77M	USD	3 Qtrs
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.12M	USD	1 Quarter
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.74M	USD	3 Qtrs
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.14M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$29.65M	USD	3 Qtrs
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$9.73M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$31.38M	USD	3 Qtrs
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$10.24M	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-30.00K	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-15.69M	USD	3 Qtrs
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-3.49M	USD	1 Quarter
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-925.00K	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-220.39M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-58.41M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-75.48M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-166.18M	USD	3 Qtrs
Balances	`StockholdersEquity`	$764.30M	USD	Point-in-time
Balances	`StockholdersEquity`	$461.41M	USD	Point-in-time
Balances	`StockholdersEquity`	$507.25M	USD	Point-in-time
Balances	`StockholdersEquity`	$377.75M	USD	Point-in-time
Balances	`StockholdersEquity`	$563.82M	USD	Point-in-time
Balances	`StockholdersEquity`	$630.52M	USD	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.