10-K Filing

REGENXBIO INC. CIK: 1590877 FY 2023

Filing Information

Form Type	10-K
Accession Number	`0000950170-24-021161`
Period End Date	20231231
Filing Date	20240227
Fiscal Year	2023
Fiscal Period	FY
XBRL Instance	rgnx-20231231_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 84 Income Statement 66 Cash Flow Statement 109 Stockholders Equity 26

Balance Sheet 84 line items

Line Item	Tag	Value	Unit	Period
Accounts receivable, allowance for credit loss, current	`AllowanceForDoubtfulAccountsReceivableCurrent`	$4.59M	USD	Point-in-time
Accounts receivable, allowance for credit loss, current	`AllowanceForDoubtfulAccountsReceivableCurrent`	$4.15M	USD	Point-in-time
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	10.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$96.95M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$34.52M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$345.21M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$240.74M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$267.69M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Accounts receivable (net of allowance of $4,587 as of December 31, 2023)	`AccountsReceivableNetCurrent`	$28.08M	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Accounts receivable (net of allowance of $4,587 as of December 31, 2023)	`AccountsReceivableNetCurrent`	$24.79M	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$13.90M	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$14.52M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$9.35M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Other current assets	`OtherAssetsCurrent`	$20.40M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$415.98M	USD	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	43.30M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	44.05M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$334.97M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	44.05M	shares	Point-in-time
Marketable securities	`MarketableSecuritiesNoncurrent`	$38.87M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesNoncurrent`	$200.56M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	43.30M	shares	Point-in-time
Accounts receivable (net of allowance of $4,152 as of December 31, 2022)	`AccountsReceivableNetNoncurrent`	$701.00K	USD	Point-in-time
Accounts receivable (net of allowance of $4,152 as of December 31, 2022)	`AccountsReceivableNetNoncurrent`	$1.50M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$132.10M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$141.69M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$65.12M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$60.49M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$2.03M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$2.03M	USD	Point-in-time
Restricted cash	`RestrictedCashAndCashEquivalentsNoncurrent`	$2.03M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$4.81M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$6.40M	USD	Point-in-time
Total assets	`Assets`	$833.27M	USD	Point-in-time
Total assets	`Assets`	$573.97M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$27.21M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$22.79M	USD	Point-in-time
Accrued expenses and other current liabilities	`AccruedExpensesAndOtherCurrentLiabilities`	$49.70M	USD	Point-in-time
Accrued expenses and other current liabilities	`AccruedExpensesAndOtherCurrentLiabilities`	$46.79M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$148.00K	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$1.83M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$6.00M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.07M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesCurrent`	$48.60M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesCurrent`	$50.57M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$130.43M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$130.27M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$82.22M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$88.80M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesNonCurrent`	$89.00M	USD	Point-in-time
Liability related to sale of future royalties	`LiabilityRelatedToSaleOfFutureRoyaltiesNonCurrent`	$43.48M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$6.25M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$8.83M	USD	Point-in-time
Total liabilities	`Liabilities`	$317.07M	USD	Point-in-time
Total liabilities	`Liabilities`	$262.23M	USD	Point-in-time
Commitments and contingencies (Note 8)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 8)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValue`	-	USD	Point-in-time
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValue`	-	USD	Point-in-time
Common stock; $0.0001 par value; 100,000 shares authorized at December 31, 2023 and 2022; 44,046 and 43,299 shares issued and outstanding at December 31, 2023 and 2022, respectively	`CommonStockValue`	$4.00K	USD	Point-in-time
Common stock; $0.0001 par value; 100,000 shares authorized at December 31, 2023 and 2022; 44,046 and 43,299 shares issued and outstanding at December 31, 2023 and 2022, respectively	`CommonStockValue`	$4.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.02B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$973.14M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-4.43M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-15.40M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-705.05M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-441.55M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$377.75M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$311.74M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$764.30M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$516.20M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$833.27M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$573.97M	USD	Point-in-time

Income Statement 66 line items

Line Item	Tag	Value	Unit	Period
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$470.35M	USD	Annual
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$112.72M	USD	Annual
Revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$90.24M	USD	Annual
Cost of revenues	`CostOfGoodsAndServicesSold`	$51.83M	USD	Annual
Cost of revenues	`CostOfGoodsAndServicesSold`	$54.55M	USD	Annual
Cost of revenues	`CostOfGoodsAndServicesSold`	$37.21M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$181.44M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$232.27M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$242.45M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$88.49M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$85.28M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$79.33M	USD	Annual
Credit losses (recoveries)	`ProvisionForOtherCreditLosses`	$-2.57M	USD	Annual
Credit losses (recoveries)	`ProvisionForOtherCreditLosses`	-	USD	Annual
Credit losses (recoveries)	`ProvisionForOtherCreditLosses`	-	USD	Annual
Other operating expenses (income)	`OtherOperatingExpensesIncome`	$-397.00K	USD	Annual
Other operating expenses (income)	`OtherOperatingExpensesIncome`	$-333.00K	USD	Annual
Other operating expenses (income)	`OtherOperatingExpensesIncome`	$6.68M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$375.60M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$310.37M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$358.37M	USD	Annual
Income (loss) from operations	`OperatingIncomeLoss`	$-262.88M	USD	Annual
Income (loss) from operations	`OperatingIncomeLoss`	$159.98M	USD	Annual
Income (loss) from operations	`OperatingIncomeLoss`	$-268.13M	USD	Annual
Interest income from licensing	`InterestIncomeFromLicencing`	$25.00K	USD	Annual
Interest income from licensing	`InterestIncomeFromLicencing`	$342.00K	USD	Annual
Interest income from licensing	`InterestIncomeFromLicencing`	$719.00K	USD	Annual
Investment income	`InvestmentIncomeNet`	$5.38M	USD	Annual
Investment income	`InvestmentIncomeNet`	$6.83M	USD	Annual
Investment income	`InvestmentIncomeNet`	$11.32M	USD	Annual
Interest expense	`InterestExpense`	$23.25M	USD	Annual
Interest expense	`InterestExpense`	$26.28M	USD	Annual
Interest expense	`InterestExpense`	$6.86M	USD	Annual
Total other income (expense)	`NonoperatingIncomeExpense`	$-18.73M	USD	Annual
Total other income (expense)	`NonoperatingIncomeExpense`	$-17.53M	USD	Annual
Total other income (expense)	`NonoperatingIncomeExpense`	$4.48M	USD	Annual
Income (loss) before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-263.65M	USD	Annual
Income (loss) before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$141.25M	USD	Annual
Income (loss) before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-280.40M	USD	Annual
Income Tax Benefit (Expense)	`IncomeTaxExpenseBenefit`	$13.41M	USD	Annual
Income Tax Benefit (Expense)	`IncomeTaxExpenseBenefit`	$-152.00K	USD	Annual
Income Tax Benefit (Expense)	`IncomeTaxExpenseBenefit`	$-84.00K	USD	Annual
Net income (loss)	`NetIncomeLoss`	$127.84M	USD	Annual
Net income (loss)	`NetIncomeLoss`	$-263.49M	USD	Annual
Net income (loss)	`NetIncomeLoss`	$-280.32M	USD	Annual
Unrealized gain (loss) on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-2.21M	USD	Annual
Unrealized gain (loss) on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$10.97M	USD	Annual
Unrealized gain (loss) on available-for-sale securities, net	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-12.83M	USD	Annual
Total other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$-2.21M	USD	Annual
Total other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$-12.83M	USD	Annual
Total other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$10.97M	USD	Annual
Comprehensive income (loss)	`ComprehensiveIncomeNetOfTax`	$125.63M	USD	Annual
Comprehensive income (loss)	`ComprehensiveIncomeNetOfTax`	$-293.15M	USD	Annual
Comprehensive income (loss)	`ComprehensiveIncomeNetOfTax`	$-252.52M	USD	Annual
Basic	`EarningsPerShareBasic`	$-6.50	USD	Annual
Basic	`EarningsPerShareBasic`	$-6.02	USD	Annual
Basic	`EarningsPerShareBasic`	$3.01	USD	Annual
Diluted	`EarningsPerShareDiluted`	$-6.50	USD	Annual
Diluted	`EarningsPerShareDiluted`	$-6.02	USD	Annual
Diluted	`EarningsPerShareDiluted`	$2.91	USD	Annual
Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	43.73M	shares	Annual
Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	42.44M	shares	Annual
Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	43.15M	shares	Annual
Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	43.91M	shares	Annual
Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	43.15M	shares	Annual
Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	43.73M	shares	Annual

Cash Flow Statement 109 line items

Line Item	Tag	Value	Unit	Period
Net income (loss)	`ProfitLoss`	$127.84M	USD	Annual
Net income (loss)	`ProfitLoss`	$-263.49M	USD	Annual
Net income (loss)	`ProfitLoss`	$-280.32M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$40.27M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$38.81M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$40.79M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$17.32M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$12.91M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$9.56M	USD	Annual
Provision for credit losses (recoveries)	`ProvisionForOtherCreditLosses`	$-2.57M	USD	Annual
Provision for credit losses (recoveries)	`ProvisionForOtherCreditLosses`	-	USD	Annual
Provision for credit losses (recoveries)	`ProvisionForOtherCreditLosses`	-	USD	Annual
Net amortization of premiums on marketable debt securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-5.84M	USD	Annual
Net amortization of premiums on marketable debt securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-4.71M	USD	Annual
Net amortization of premiums on marketable debt securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-687.00K	USD	Annual
Net realized loss (gain) on investments	`RealizedInvestmentGainsLosses`	$-79.00K	USD	Annual
Net realized loss (gain) on investments	`RealizedInvestmentGainsLosses`	$5.19M	USD	Annual
Net realized loss (gain) on investments	`RealizedInvestmentGainsLosses`	$2.21M	USD	Annual
Non-cash interest expense	`NonCashInterestExpense`	$137.00K	USD	Annual
Non-cash interest expense	`NonCashInterestExpense`	$4.64M	USD	Annual
Non-cash interest expense	`NonCashInterestExpense`	$-414.00K	USD	Annual
Other non-cash adjustments	`OtherNoncashIncomeExpense`	$-319.00K	USD	Annual
Other non-cash adjustments	`OtherNoncashIncomeExpense`	$-231.00K	USD	Annual
Other non-cash adjustments	`OtherNoncashIncomeExpense`	$281.00K	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-3.94M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-14.12M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-4.82M	USD	Annual
Prepaid expenses	`IncreaseDecreaseInPrepaidExpense`	$620.00K	USD	Annual
Prepaid expenses	`IncreaseDecreaseInPrepaidExpense`	$8.25M	USD	Annual
Prepaid expenses	`IncreaseDecreaseInPrepaidExpense`	$-4.85M	USD	Annual
Other current assets	`IncreaseDecreaseInOtherCurrentAssets`	$10.55M	USD	Annual
Other current assets	`IncreaseDecreaseInOtherCurrentAssets`	$-247.00K	USD	Annual
Other current assets	`IncreaseDecreaseInOtherCurrentAssets`	$7.31M	USD	Annual
Operating lease right-of-use assets	`IncreaseDecreaseInOperatingLeaseRightOfUseAssets`	$-4.87M	USD	Annual
Operating lease right-of-use assets	`IncreaseDecreaseInOperatingLeaseRightOfUseAssets`	$-5.76M	USD	Annual
Operating lease right-of-use assets	`IncreaseDecreaseInOperatingLeaseRightOfUseAssets`	$-4.45M	USD	Annual
Other assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$2.27M	USD	Annual
Other assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$-1.59M	USD	Annual
Other assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$-31.00K	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayableTrade`	$18.79M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayableTrade`	$-2.30M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayableTrade`	$-2.79M	USD	Annual
Accrued expenses and other current liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$2.45M	USD	Annual
Accrued expenses and other current liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$-25.62M	USD	Annual
Accrued expenses and other current liabilities	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$29.91M	USD	Annual
Deferred revenue	`IncreaseDecreaseInDeferredRevenue`	$-1.51M	USD	Annual
Deferred revenue	`IncreaseDecreaseInDeferredRevenue`	$-899.00K	USD	Annual
Deferred revenue	`IncreaseDecreaseInDeferredRevenue`	$-1.17M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-6.64M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-544.00K	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$12.07M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$8.11M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-2.52M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$289.00K	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$218.88M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-207.49M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-218.41M	USD	Annual
Purchases of marketable debt securities	`PaymentsToAcquireMarketableSecurities`	$498.14M	USD	Annual
Purchases of marketable debt securities	`PaymentsToAcquireMarketableSecurities`	$184.88M	USD	Annual
Purchases of marketable debt securities	`PaymentsToAcquireMarketableSecurities`	$86.56M	USD	Annual
Maturities of marketable debt securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$203.15M	USD	Annual
Maturities of marketable debt securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$170.09M	USD	Annual
Maturities of marketable debt securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$285.49M	USD	Annual
Sales of equity securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$1.98M	USD	Annual
Sales of equity securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$524.00K	USD	Annual
Sales of equity securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$5.59M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$84.17M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$30.72M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$9.96M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-11.93M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$190.94M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-406.64M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromStockOptionsExercised`	$2.80M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromStockOptionsExercised`	$4.28M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromStockOptionsExercised`	$1.52M	USD	Annual
Taxes paid related to net settlement of stock-based awards	`TaxesPaidRelatedToNetSettlementOfStockBasedAwards`	$419.00K	USD	Annual
Taxes paid related to net settlement of stock-based awards	`TaxesPaidRelatedToNetSettlementOfStockBasedAwards`	$284.00K	USD	Annual
Taxes paid related to net settlement of stock-based awards	`TaxesPaidRelatedToNetSettlementOfStockBasedAwards`	$2.00K	USD	Annual
Proceeds from issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans`	$1.74M	USD	Annual
Proceeds from issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans`	$1.83M	USD	Annual
Proceeds from issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans`	$1.77M	USD	Annual
Proceeds from public offering of common stock, net of underwriting discounts and commissions	`ProceedsFromIssuancesOfCommonStockNetOfUnderwritingDiscountsAndCommissions`	$216.44M	USD	Annual
Proceeds from private placement of common stock, net of issuance costs	`ProceedsFromIssuanceOfPrivatePlacement`	$4.87M	USD	Annual
Offering expenses related to at-the-market offering program	`OfferingExpensesRelatedToAtTheMarketOfferingProgram`	$470.00K	USD	Annual
Issuance costs for public offering of common stock	`PaymentsOfStockIssuanceCosts`	$379.00K	USD	Annual
Transaction costs for sale of future royalties	`PaymentsOfTransactionCostsForSaleOfFutureLoyalties`	$265.00K	USD	Annual
Repayments under liability related to sale of future royalties, net of imputed interest	`RepaymentsUnderLiabilityRelatedToSaleOfFutureRoyalties`	$33.10M	USD	Annual
Repayments under liability related to sale of future royalties, net of imputed interest	`RepaymentsUnderLiabilityRelatedToSaleOfFutureRoyalties`	$42.30M	USD	Annual
Repayments under liability related to sale of future royalties, net of imputed interest	`RepaymentsUnderLiabilityRelatedToSaleOfFutureRoyalties`	$26.59M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-28.84M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-34.97M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$195.25M	USD	Annual
Net increase (decrease) in cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$7.48M	USD	Annual
Net increase (decrease) in cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-248.26M	USD	Annual
Net increase (decrease) in cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-62.43M	USD	Annual
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$36.55M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$339.76M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$347.24M	USD	Point-in-time
Beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$98.98M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$36.55M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$339.76M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$347.24M	USD	Point-in-time
End of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$98.98M	USD	Point-in-time
Cash paid (received) for income taxes	`IncomeTaxesPaidNet`	$-142.00K	USD	Annual
Cash paid (received) for income taxes	`IncomeTaxesPaidNet`	$6.00M	USD	Annual
Cash paid (received) for income taxes	`IncomeTaxesPaidNet`	$11.81M	USD	Annual
Cash paid for imputed interest under liability related to sale of future royalties	`CashPaidForImputedInterestUnderLiabilityRelatedToSaleOfFutureRoyalties`	$23.12M	USD	Annual
Cash paid for imputed interest under liability related to sale of future royalties	`CashPaidForImputedInterestUnderLiabilityRelatedToSaleOfFutureRoyalties`	$21.64M	USD	Annual
Cash paid for imputed interest under liability related to sale of future royalties	`CashPaidForImputedInterestUnderLiabilityRelatedToSaleOfFutureRoyalties`	$7.28M	USD	Annual

Stockholders Equity 26 line items

Line Item	Tag	Value	Unit	Period
Balances	`StockholdersEquity`	$377.75M	USD	Point-in-time
Balances	`StockholdersEquity`	$311.74M	USD	Point-in-time
Balances	`StockholdersEquity`	$764.30M	USD	Point-in-time
Balances	`StockholdersEquity`	$516.20M	USD	Point-in-time
Issuance of common stock upon public offering, net of transaction costs	`StockIssuedDuringPeriodValueNewIssues`	$216.06M	USD	Annual
Vesting of restricted stock units, net of tax	`VestingOfRestrictedStockUnits`	$-419.00K	USD	Annual
Vesting of restricted stock units, net of tax	`VestingOfRestrictedStockUnits`	$-284.00K	USD	Annual
Exercise of stock options, net of tax	`StockIssuedDuringPeriodValueStockOptionsExercised`	$4.28M	USD	Annual
Exercise of stock options, net of tax	`StockIssuedDuringPeriodValueStockOptionsExercised`	$1.52M	USD	Annual
Exercise of stock options, net of tax	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.80M	USD	Annual
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.74M	USD	Annual
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.77M	USD	Annual
Issuance of common stock under employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.83M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$40.79M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$38.81M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$40.27M	USD	Annual
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-12.83M	USD	Annual
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$10.97M	USD	Annual
Unrealized loss on available-for-sale securities, net	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.21M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$127.84M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-263.49M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-280.32M	USD	Annual
Balances	`StockholdersEquity`	$377.75M	USD	Point-in-time
Balances	`StockholdersEquity`	$311.74M	USD	Point-in-time
Balances	`StockholdersEquity`	$764.30M	USD	Point-in-time
Balances	`StockholdersEquity`	$516.20M	USD	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.