10-K Filing

TWIST BIOSCIENCE CORP CIK: 1581280 FY 2021

Filing Information

Form Type	10-K
Accession Number	`0001104659-21-142700`
Period End Date	20210930
Filing Date	20211123
Fiscal Year	2021
Fiscal Period	FY
XBRL Instance	twst-20210930x10k_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 69 Income Statement 53 Cash Flow Statement 111 Stockholders Equity 31

Balance Sheet 69 line items

Line Item	Tag	Value	Unit	Period
Common stock, par value	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, share authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Common stock, share authorized	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$93.67M	USD	Point-in-time
Common stock, share issued	`CommonStockSharesIssued`	45.08M	shares	Point-in-time
Common stock, share issued	`CommonStockSharesIssued`	49.50M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$465.83M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$12.03M	USD	Point-in-time
Common stock, share outstanding	`CommonStockSharesOutstanding`	49.50M	shares	Point-in-time
Common stock, share outstanding	`CommonStockSharesOutstanding`	45.08M	shares	Point-in-time
Short-term investments	`ShortTermInvestments`	$196.34M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$28.55M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$26.38M	USD	Point-in-time
Inventories	`InventoryNet`	$12.29M	USD	Point-in-time
Inventories	`InventoryNet`	$31.80M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$8.28M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$6.20M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$546.50M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$334.87M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$25.47M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$44.12M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$33.70M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$61.58M	USD	Point-in-time
Goodwill	`Goodwill`	$22.43M	USD	Point-in-time
Goodwill	`Goodwill`	$1.14M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$307.00K	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$18.26M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$579.00K	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$1.53M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$2.82M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$7.67M	USD	Point-in-time
Total assets	`Assets`	$398.88M	USD	Point-in-time
Total assets	`Assets`	$702.10M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$4.83M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$14.90M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$3.90M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$6.44M	USD	Point-in-time
Accrued compensation	`EmployeeRelatedLiabilitiesCurrent`	$14.95M	USD	Point-in-time
Accrued compensation	`EmployeeRelatedLiabilitiesCurrent`	$22.33M	USD	Point-in-time
Current portion of operating lease liability	`OperatingLeaseLiabilityCurrent`	$8.21M	USD	Point-in-time
Current portion of operating lease liability	`OperatingLeaseLiabilityCurrent`	$6.41M	USD	Point-in-time
Current portion of long-term debt	`LongTermDebtCurrent`	$3.33M	USD	Point-in-time
Current portion of long-term debt	`LongTermDebtCurrent`	$1.55M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$9.62M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$2.61M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$36.03M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$63.05M	USD	Point-in-time
Operating lease liability, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$53.16M	USD	Point-in-time
Operating lease liability, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$24.84M	USD	Point-in-time
Long-term debt, net of current portion	`LongTermDebtNoncurrent`	$1.40M	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$351.00K	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$5.07M	USD	Point-in-time
Total liabilities	`Liabilities`	$62.62M	USD	Point-in-time
Total liabilities	`Liabilities`	$121.28M	USD	Point-in-time
Common stock, $0.00001 par value-100,000 and 100,000 shares authorized at September 30, 2021 and 2020, respectively; 49,499 and 45,083 shares issued and outstanding at September 30, 2021 and 2020, respectively	`CommonStockValue`	-	USD	Point-in-time
Common stock, $0.00001 par value-100,000 and 100,000 shares authorized at September 30, 2021 and 2020, respectively; 49,499 and 45,083 shares issued and outstanding at September 30, 2021 and 2020, respectively	`CommonStockValue`	-	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$794.63M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$1.19B	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$87.00K	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$546.00K	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-610.55M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-458.45M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$336.26M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$-201.42M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$580.82M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$152.08M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$702.10M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$398.88M	USD	Point-in-time

Income Statement 53 line items

Line Item	Tag	Value	Unit	Period
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$132.33M	USD	Annual
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$90.10M	USD	Annual
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$54.38M	USD	Annual
Cost of revenues	`CostOfRevenue`	$47.43M	USD	Annual
Cost of revenues	`CostOfRevenue`	$80.62M	USD	Annual
Cost of revenues	`CostOfRevenue`	$61.41M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$43.01M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$35.68M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$69.07M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$103.27M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$135.90M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$80.13M	USD	Annual
Change in fair value of contingent consideration and indemnity holdback	`ChangeInFairValueOfAcquisitionConsideration`	$-534.00K	USD	Annual
Litigation settlement	`LitigationSettlementExpense`	$22.50M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$163.24M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$230.18M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$285.06M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-108.85M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-152.73M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-140.08M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$435.00K	USD	Annual
Interest income	`InvestmentIncomeInterest`	$3.03M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$1.50M	USD	Annual
Interest expense	`InterestExpense`	$787.00K	USD	Annual
Interest expense	`InterestExpense`	$367.00K	USD	Annual
Interest expense	`InterestExpense`	$1.29M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-265.00K	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-182.00K	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-1.37M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-107.38M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-154.03M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-139.55M	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$292.00K	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$-1.93M	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$382.00K	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-139.93M	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-107.67M	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-152.10M	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-34.00K	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-14.00K	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$49.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$473.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$45.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-60.00K	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-151.64M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-140.03M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-107.58M	USD	Annual
Net loss per share attributable to common stockholders-basic and diluted (in dollars per share)	`EarningsPerShareBasicAndDiluted`	$-3.92	USD	Annual
Net loss per share attributable to common stockholders-basic and diluted (in dollars per share)	`EarningsPerShareBasicAndDiluted`	$-3.57	USD	Annual
Net loss per share attributable to common stockholders-basic and diluted (in dollars per share)	`EarningsPerShareBasicAndDiluted`	$-3.15	USD	Annual
Weighted average shares used in computing net loss per share attributable to common stockholders (in shares)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	39.19M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholders (in shares)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	48.25M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholders (in shares)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	27.46M	shares	Annual

Cash Flow Statement 111 line items

Line Item	Tag	Value	Unit	Period
Net loss	`ProfitLoss`	$-152.10M	USD	Annual
Net loss	`ProfitLoss`	$-107.67M	USD	Annual
Net loss	`ProfitLoss`	$-139.93M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$9.75M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$6.11M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$6.68M	USD	Annual
Non-cash lease expense	`OperatingLeaseImpairmentLoss`	$-1.04M	USD	Annual
Non-cash lease expense	`OperatingLeaseImpairmentLoss`	$2.24M	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-2.00K	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-189.00K	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$17.10M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$37.00M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$11.17M	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-593.00K	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$214.00K	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$1.25M	USD	Annual
Realized gain on investments	`RealizedInvestmentGainsLosses`	$5.00K	USD	Annual
Allowance for doubtful accounts	`ProvisionForDoubtfulAccounts`	$40.00K	USD	Annual
Change in fair value of contingent consideration and indemnity holdback	`ChangeInFairValueOfAcquisitionConsideration`	$-534.00K	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$233.00K	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$152.00K	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$67.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$81.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$282.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$184.00K	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$2.20M	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$14.27M	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$6.68M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$19.49M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$4.96M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$1.30M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.68M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-746.00K	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.06M	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$4.65M	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$2.06M	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$554.00K	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$3.28M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$8.54M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-5.51M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$-2.65M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$3.12M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$4.21M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$7.39M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$4.46M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$5.06M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$1.98M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-28.00K	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-247.00K	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-87.94M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-142.25M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-112.24M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$9.87M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$14.76M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$27.06M	USD	Annual
Proceeds from sale of property and equipment	`ProceedsFromSaleOfPropertyPlantAndEquipment`	$21.00K	USD	Annual
Business acquisition, net of cash acquired	`PaymentsToAcquireBusinessesNetOfCashAcquired`	$483.00K	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$58.80M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$177.57M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$202.88M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$87.50M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$242.49M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$98.10M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$156.16M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-114.65M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-104.81M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$2.17M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$10.49M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$14.56M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$323.86M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$295.56M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$156.21M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$3.43M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$4.94M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$2.70M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$2.50M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$3.33M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$3.33M	USD	Annual
Repurchases of common stock for income tax withholding	`PaymentsToRepurchasesOfCommonStockForTaxWithholding`	$10.85M	USD	Annual
Repurchases of common stock for income tax withholding	`PaymentsToRepurchasesOfCommonStockForTaxWithholding`	$2.42M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$303.73M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$158.58M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$329.18M	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$30.00K	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$20.00K	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$21.00K	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-34.14M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$46.85M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$373.11M	USD	Annual
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$47.40M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$81.54M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$94.25M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$467.36M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$47.40M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$81.54M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$94.25M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$467.36M	USD	Point-in-time
Interest paid	`InterestPaidNet`	$779.00K	USD	Annual
Interest paid	`InterestPaidNet`	$438.00K	USD	Annual
Interest paid	`InterestPaidNet`	$167.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$172.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$291.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$101.00K	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$1.33M	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$170.00K	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$2.01M	USD	Annual
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$33.62M	USD	Annual
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$3.72M	USD	Annual
Conversion of redeemable convertible preferred stock warrant liability to equity	`ConversionOfConvertiblePreferredStockWarrant`	$631.00K	USD	Annual
Conversion of redeemable convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$290.46M	USD	Annual
Issuance of common stock in connection with the iGenomX acquisition	`StockIssued1`	$26.77M	USD	Annual

Stockholders Equity 31 line items

Line Item	Tag	Value	Unit	Period
Beginning Balance	`StockholdersEquity`	$336.26M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$-201.42M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$580.82M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$152.08M	USD	Point-in-time
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$323.86M	USD	Annual
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$153.85M	USD	Annual
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$295.56M	USD	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$3.43M	USD	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$4.94M	USD	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.70M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$14.47M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.26M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$10.54M	USD	Annual
Conversion of redeemable convertible preferred stock warrant liability to equity	`ConversionOfConvertiblePreferredStockWarrant`	$631.00K	USD	Annual
Conversion of redeemable convertible preferred stock to common stock	`StockIssuedDuringPeriodValueConversionOfConvertibleSecurities`	$290.46M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$17.10M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$37.00M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$11.17M	USD	Annual
Business acquisition	`StockIssuedDuringPeriodValueAcquisitions`	$26.77M	USD	Annual
Other comprehensive income	`OtherComprehensiveIncomeLossNetOfTax`	$94.00K	USD	Annual
Other comprehensive income	`OtherComprehensiveIncomeLossNetOfTax`	$-94.00K	USD	Annual
Other comprehensive income	`OtherComprehensiveIncomeLossNetOfTax`	$459.00K	USD	Annual
Repurchases of common stock for income tax withholding	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$-10.85M	USD	Annual
Repurchases of common stock for income tax withholding	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$-2.42M	USD	Annual
Net loss	`ProfitLoss`	$-152.10M	USD	Annual
Net loss	`ProfitLoss`	$-107.67M	USD	Annual
Net loss	`ProfitLoss`	$-139.93M	USD	Annual
Ending Balance	`StockholdersEquity`	$336.26M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$-201.42M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$580.82M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$152.08M	USD	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.