10-K Filing

AGIOS PHARMACEUTICALS, INC. CIK: 1439222 FY 2016

Filing Information

Form Type	10-K
Accession Number	`0001193125-17-046795`
Period End Date	20161231
Filing Date	20170216
Fiscal Year	2016
Fiscal Period	FY
XBRL Instance	agio-20161231.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 70 Income Statement 50 Cash Flow Statement 85 Stockholders Equity 27 Comprehensive Income 9

Balance Sheet 70 line items

Line Item	Tag	Value	Unit	Period
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Preferred stock, shares authorized	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$14.03M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$71.56M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$160.75M	USD	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Preferred stock, shares issued	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$71.76M	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$380.56M	USD	Point-in-time
Preferred stock, shares outstanding	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$245.24M	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Collaboration receivable - related party	`DueFromRelatedPartiesCurrent`	$4.89M	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Collaboration receivable - related party	`DueFromRelatedPartiesCurrent`	$8.22M	USD	Point-in-time
Tenant improvement and other receivables	`AccountsAndOtherReceivablesNetCurrent`	$3.43M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Tenant improvement and other receivables	`AccountsAndOtherReceivablesNetCurrent`	$3.37M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	42.22M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	37.70M	shares	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$10.26M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$8.73M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	42.22M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$559.89M	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	37.70M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$337.33M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesNoncurrent`	$58.91M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesNoncurrent`	$32.25M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$25.34M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$23.22M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$1.61M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$611.00K	USD	Point-in-time
Total assets	`Assets`	$420.06M	USD	Point-in-time
Total assets	`Assets`	$619.09M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$17.11M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$14.75M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$16.00M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$32.00M	USD	Point-in-time
Deferred revenue - related party	`DeferredRevenueCurrent`	$35.91M	USD	Point-in-time
Deferred revenue - related party	`DeferredRevenueCurrent`	$19.66M	USD	Point-in-time
Deferred rent	`DeferredRentCreditCurrent`	$3.41M	USD	Point-in-time
Deferred rent	`DeferredRentCreditCurrent`	$2.48M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$52.89M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$88.43M	USD	Point-in-time
Deferred revenue, net of current portion - related party	`DeferredRevenueNoncurrent`	$4.70M	USD	Point-in-time
Deferred revenue, net of current portion - related party	`DeferredRevenueNoncurrent`	$154.30M	USD	Point-in-time
Deferred rent, net of current portion	`DeferredRentCreditNoncurrent`	$17.36M	USD	Point-in-time
Deferred rent, net of current portion	`DeferredRentCreditNoncurrent`	$17.77M	USD	Point-in-time
Commitments and contingencies (Note 6)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 6)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at December 31, 2016 and 2015	`PreferredStockValue`	-	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at December 31, 2016 and 2015	`PreferredStockValue`	-	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized and 42,220,444 and 37,696,502 shares issued and outstanding at December 31, 2016 and 2015, respectively	`CommonStockValue`	$38.00K	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized and 42,220,444 and 37,696,502 shares issued and outstanding at December 31, 2016 and 2015, respectively	`CommonStockValue`	$42.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$630.08M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$842.01M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-313.00K	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-318.00K	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-284.68M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-483.15M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$345.12M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$358.59M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$424.37M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$131.48M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$420.06M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$619.09M	USD	Point-in-time

Income Statement 50 line items

Line Item	Tag	Value	Unit	Period
Cost reimbursement from related party	`ReimbursementOfResearchAndDevelopmentRelatedPartyCost`	-	USD	Annual
Collaboration revenue - related party	`RevenueFromRelatedParties`	$59.12M	USD	Annual
Collaboration revenue - related party	`RevenueFromRelatedParties`	$69.89M	USD	Annual
Cost reimbursement from related party	`ReimbursementOfResearchAndDevelopmentRelatedPartyCost`	$19.71M	USD	Annual
Cost reimbursement from related party	`ReimbursementOfResearchAndDevelopmentRelatedPartyCost`	$25.17M	USD	Annual
Collaboration revenue - related party	`RevenueFromRelatedParties`	$65.36M	USD	Annual
Research and development (net of $19,714 and $25,173 of cost reimbursement from related party for the years ended December 31, 2016 and 2015, respectively)	`ResearchAndDevelopmentExpense`	$141.83M	USD	Annual
Research and development (net of $19,714 and $25,173 of cost reimbursement from related party for the years ended December 31, 2016 and 2015, respectively)	`ResearchAndDevelopmentExpense`	$100.37M	USD	Annual
Research and development (net of $19,714 and $25,173 of cost reimbursement from related party for the years ended December 31, 2016 and 2015, respectively)	`ResearchAndDevelopmentExpense`	$220.16M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$35.99M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$19.12M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$50.71M	USD	Annual
Total operating expenses	`OperatingExpenses`	$119.49M	USD	Annual
Total operating expenses	`OperatingExpenses`	$177.82M	USD	Annual
Total operating expenses	`OperatingExpenses`	$270.88M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-32.13M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-40.90M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-200.99M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-118.70M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-56.47M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-40.48M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-57.41M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-5.20M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-23.59M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-54.13M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-63.51M	USD	1 Quarter
Interest income	`InvestmentIncomeInterest`	$968.00K	USD	Annual
Interest income	`InvestmentIncomeInterest`	$203.00K	USD	Annual
Interest income	`InvestmentIncomeInterest`	$2.51M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-198.47M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-53.93M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-117.73M	USD	Annual
Benefit from income taxes	`IncomeTaxExpenseBenefit`	$-426.00K	USD	Annual
Net loss	`NetIncomeLoss`	$-117.73M	USD	Annual
Net loss	`NetIncomeLoss`	$-198.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-53.50M	USD	Annual
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.07	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-0.85	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-3.15	USD	Annual
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.34	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-5.07	USD	Annual
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.47	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.59	USD	Annual
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-0.13	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.63	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-1.08	USD	1 Quarter
Net loss per share - basic and diluted	`EarningsPerShareBasicAndDiluted`	$-0.61	USD	1 Quarter
Weighted-average number of common shares used in net loss per share - basic and diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	33.67M	shares	Annual
Weighted-average number of common shares used in net loss per share - basic and diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	37.43M	shares	Annual
Weighted-average number of common shares used in net loss per share - basic and diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	39.13M	shares	Annual

Cash Flow Statement 85 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-117.73M	USD	Annual
Net loss	`NetIncomeLoss`	$-198.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-53.50M	USD	Annual
Depreciation	`Depreciation`	$3.34M	USD	Annual
Depreciation	`Depreciation`	$5.71M	USD	Annual
Depreciation	`Depreciation`	$1.37M	USD	Annual
Net loss on disposal of fixed assets	`GainLossOnDispositionOfAssets1`	$-33.00K	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$11.51M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$31.96M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$42.09M	USD	Annual
Net amortization of premiums and discounts on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-539.00K	USD	Annual
Net amortization of premiums and discounts on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-773.00K	USD	Annual
Net amortization of premiums and discounts on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-538.00K	USD	Annual
Collaboration receivable - related party	`IncreaseDecreaseInDueFromRelatedPartiesCurrent`	$6.02M	USD	Annual
Collaboration receivable - related party	`IncreaseDecreaseInDueFromRelatedPartiesCurrent`	$-3.34M	USD	Annual
Collaboration receivable - related party	`IncreaseDecreaseInDueFromRelatedPartiesCurrent`	$1.73M	USD	Annual
Tenant improvement and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$1.04M	USD	Annual
Tenant improvement and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$2.33M	USD	Annual
Tenant improvement and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$-275.00K	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.77M	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.88M	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.69M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$3.50M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$4.21M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$7.58M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$5.23M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$1.63M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$16.85M	USD	Annual
Deferred rent	`IncreaseDecreaseInDeferredCharges`	$-3.69M	USD	Annual
Deferred rent	`IncreaseDecreaseInDeferredCharges`	$-1.35M	USD	Annual
Deferred rent	`IncreaseDecreaseInDeferredCharges`	$-15.80M	USD	Annual
Refundable income taxes and income taxes payable	`IncreaseDecreaseInAccruedIncomeTaxesPayable`	$-5.30M	USD	Annual
Refundable income taxes and income taxes payable	`IncreaseDecreaseInAccruedIncomeTaxesPayable`	$3.84M	USD	Annual
Deferred revenue - related party	`IncreaseDecreaseInDeferredRevenue`	$-19.23M	USD	Annual
Deferred revenue - related party	`IncreaseDecreaseInDeferredRevenue`	$165.85M	USD	Annual
Deferred revenue - related party	`IncreaseDecreaseInDeferredRevenue`	$-14.05M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$-59.35M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$38.56M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$-76.95M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecurities`	$506.07M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecurities`	$837.22M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecurities`	$353.18M	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$505.53M	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$501.65M	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$396.63M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$20.16M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$2.22M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$9.91M	USD	Annual
Release of restricted cash	`DecreaseInRestrictedCash`	$571.00K	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$128.31M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$-119.35M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$-333.34M	USD	Annual
Proceeds from public offering of common stock, net of commissions	`ProceedsFromIssuanceOfCommonStock`	$333.58M	USD	Annual
Proceeds from public offering of common stock, net of commissions	`ProceedsFromIssuanceOfCommonStock`	$162.15M	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	$720.00K	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	$207.00K	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	$230.00K	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan and vesting of restricted stock units	`ProceedsFromStockOptionsExercised`	$6.58M	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan and vesting of restricted stock units	`ProceedsFromStockOptionsExercised`	$2.30M	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan and vesting of restricted stock units	`ProceedsFromStockOptionsExercised`	$7.86M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivitiesContinuingOperations`	$6.37M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivitiesContinuingOperations`	$335.16M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivitiesContinuingOperations`	$169.78M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$-57.53M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$88.99M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$57.73M	USD	Annual
Cash and cash equivalents at beginning of the period	`CashAndCashEquivalentsAtCarryingValue`	$14.03M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashAndCashEquivalentsAtCarryingValue`	$71.56M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashAndCashEquivalentsAtCarryingValue`	$160.75M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashAndCashEquivalentsAtCarryingValue`	$71.76M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashAndCashEquivalentsAtCarryingValue`	$14.03M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashAndCashEquivalentsAtCarryingValue`	$71.56M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashAndCashEquivalentsAtCarryingValue`	$160.75M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashAndCashEquivalentsAtCarryingValue`	$71.76M	USD	Point-in-time
Cash paid for income taxes	`IncomeTaxesPaid`	$5.98M	USD	Annual
Vesting of restricted stock	`VestingOfRestrictedStockValueIncreaseDecrease`	$9.00K	USD	Annual
Vesting of restricted stock	`VestingOfRestrictedStockValueIncreaseDecrease`	$6.00K	USD	Annual
Additions to property, plant and equipment included in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$2.12M	USD	Annual
Additions to property, plant and equipment included in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$2.16M	USD	Annual
Additions to property, plant and equipment included in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$73.00K	USD	Annual
Proceeds from stock option exercises in other current assets	`ProceedsFromStockOptionsExercisedInOtherCurrentAssets`	$186.00K	USD	Annual
Proceeds from stock option exercises in other current assets	`ProceedsFromStockOptionsExercisedInOtherCurrentAssets`	$32.00K	USD	Annual
Proceeds from stock option exercises in other current assets	`ProceedsFromStockOptionsExercisedInOtherCurrentAssets`	$20.00K	USD	Annual
Public offering costs in other current assets, net of amounts in accounts payable and accrued expenses	`PublicOfferingCostsInOtherCurrentAssetsNetOfAmountsInAccountsPayableAndAccruedExpenses`	$236.00K	USD	Annual
Public offering costs in other current assets, net of amounts in accounts payable and accrued expenses	`PublicOfferingCostsInOtherCurrentAssetsNetOfAmountsInAccountsPayableAndAccruedExpenses`	$230.00K	USD	Annual

Stockholders Equity 27 line items

Line Item	Tag	Value	Unit	Period
Issuance costs of common stock	`AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts`	$900.00K	USD	Annual
Beginning balance, Value	`StockholdersEquity`	$345.12M	USD	Point-in-time
Beginning balance, Value	`StockholdersEquity`	$358.59M	USD	Point-in-time
Beginning balance, Value	`StockholdersEquity`	$424.37M	USD	Point-in-time
Beginning balance, Value	`StockholdersEquity`	$131.48M	USD	Point-in-time
Unrealized gain (loss) on marketable securities	`MarketableSecuritiesUnrealizedGainLoss`	$5.00K	USD	Annual
Unrealized gain (loss) on marketable securities	`MarketableSecuritiesUnrealizedGainLoss`	$-261.00K	USD	Annual
Unrealized gain (loss) on marketable securities	`MarketableSecuritiesUnrealizedGainLoss`	$-71.00K	USD	Annual
Net loss	`NetIncomeLoss`	$-117.73M	USD	Annual
Net loss	`NetIncomeLoss`	$-198.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-53.50M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$42.09M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$11.51M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$31.57M	USD	Annual
Vesting of restricted stock, Value	`AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition`	$9.00K	USD	Annual
Vesting of restricted stock, Value	`AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition`	$6.00K	USD	Annual
Issuance of common stock upon exercise of stock options, Value	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.32M	USD	Annual
Issuance of common stock upon exercise of stock options, Value	`StockIssuedDuringPeriodValueStockOptionsExercised`	$7.70M	USD	Annual
Issuance of common stock upon exercise of stock options, Value	`StockIssuedDuringPeriodValueStockOptionsExercised`	$7.14M	USD	Annual
Issuance of common stock upon exercise of stock options and employee stock purchase plan and vesting of restricted stock units	`StockIssuedDuringPeriodSharesStockOptionsExercised`	603,359.00	shares	Annual
Issuance of stock, Value	`StockIssuedDuringPeriodValueNewIssues`	$332.62M	USD	Annual
Issuance of stock, Value	`StockIssuedDuringPeriodValueNewIssues`	$162.15M	USD	Annual
Issuance of stock, Value	`StockIssuedDuringPeriodValueNewIssues`	$29.00K	USD	Annual
Ending balance, Value	`StockholdersEquity`	$345.12M	USD	Point-in-time
Ending balance, Value	`StockholdersEquity`	$358.59M	USD	Point-in-time
Ending balance, Value	`StockholdersEquity`	$424.37M	USD	Point-in-time
Ending balance, Value	`StockholdersEquity`	$131.48M	USD	Point-in-time

Comprehensive Income 9 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-117.73M	USD	Annual
Net loss	`NetIncomeLoss`	$-198.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-53.50M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-261.00K	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$5.00K	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-71.00K	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-198.47M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-53.58M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-117.99M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.