10-Q Filing

AGIOS PHARMACEUTICALS, INC. CIK: 1439222 Q3 2019

Filing Information

Form Type	10-Q
Accession Number	`0001439222-19-000021`
Period End Date	20190930
Filing Date	20191031
Fiscal Year	2019
Fiscal Period	Q3
XBRL Instance	agio-20190930_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 81 Income Statement 44 Cash Flow Statement 71 Stockholders Equity 46 Comprehensive Income 16

Balance Sheet 81 line items

Line Item	Tag	Value	Unit	Period
Preferred stock, par value (in usd per share)	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value (in usd per share)	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, shares authorized (in shares)	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Preferred stock, shares authorized (in shares)	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$70.50M	USD	Point-in-time
Preferred stock, shares issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Preferred stock, shares issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$81.71M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesCurrent`	$370.19M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesCurrent`	$514.80M	USD	Point-in-time
Preferred stock, shares outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Preferred stock, shares outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Common stock, par value (in usd per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Accounts receivable, net	`ContractWithCustomerAssetNetCurrent`	$5.08M	USD	Point-in-time
Common stock, par value (in usd per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Accounts receivable, net	`ContractWithCustomerAssetNetCurrent`	$7.11M	USD	Point-in-time
Collaboration receivable related party	`CollaborationReceivableDuefromRelatedPartiesCurrent`	$1.84M	USD	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Collaboration receivable related party	`CollaborationReceivableDuefromRelatedPartiesCurrent`	$2.46M	USD	Point-in-time
Collaboration receivable other	`CollaborationReceivableOtherCurrent`	$670.00K	USD	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	58.88M	shares	Point-in-time
Collaboration receivable other	`CollaborationReceivableOtherCurrent`	$869.00K	USD	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	58.22M	shares	Point-in-time
Royalty receivable related party	`RoyaltyReceivableDuefromRelatedPartiesCurrent`	$2.60M	USD	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	58.88M	shares	Point-in-time
Royalty receivable related party	`RoyaltyReceivableDuefromRelatedPartiesCurrent`	$2.23M	USD	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	58.22M	shares	Point-in-time
Inventory	`InventoryNet`	$5.85M	USD	Point-in-time
Inventory	`InventoryNet`	$869.00K	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$17.17M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$19.98M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$613.78M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$490.14M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesNoncurrent`	$88.58M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesNoncurrent`	$220.12M	USD	Point-in-time
Operating lease assets	`OperatingLeaseRightOfUseAsset`	$95.83M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$24.06M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$24.32M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	-	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$238.00K	USD	Point-in-time
Total assets	`Assets`	$858.46M	USD	Point-in-time
Total assets	`Assets`	$698.62M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$21.51M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$17.88M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$46.75M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$42.15M	USD	Point-in-time
Deferred revenue related party	`ContractWithCustomerLiabilityCurrent`	$16.87M	USD	Point-in-time
Deferred revenue related party	`ContractWithCustomerLiabilityCurrent`	$32.71M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.30M	USD	Point-in-time
Deferred rent	`DeferredRentCreditCurrent`	-	USD	Point-in-time
Deferred rent	`DeferredRentCreditCurrent`	$766.00K	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$92.43M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$93.50M	USD	Point-in-time
Deferred revenue, net of current portion related party	`ContractWithCustomerLiabilityNoncurrent`	$59.81M	USD	Point-in-time
Deferred revenue, net of current portion related party	`ContractWithCustomerLiabilityNoncurrent`	$49.80M	USD	Point-in-time
Operating lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$108.10M	USD	Point-in-time
Deferred rent, net of current portion	`DeferredRentCreditNoncurrent`	$17.61M	USD	Point-in-time
Deferred rent, net of current portion	`DeferredRentCreditNoncurrent`	-	USD	Point-in-time
Total liabilities	`Liabilities`	$170.92M	USD	Point-in-time
Total liabilities	`Liabilities`	$250.32M	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at September 30, 2019 and December 31, 2018	`PreferredStockValue`	-	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized; no shares issued or outstanding at September 30, 2019 and December 31, 2018	`PreferredStockValue`	-	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized; 58,877,691 and 58,218,653 shares issued and outstanding at September 30, 2019 and December 31, 2018, respectively	`CommonStockValue`	$58.00K	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized; 58,877,691 and 58,218,653 shares issued and outstanding at September 30, 2019 and December 31, 2018, respectively	`CommonStockValue`	$59.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.79B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.86B	USD	Point-in-time
Accumulated other comprehensive income (loss)	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$464.00K	USD	Point-in-time
Accumulated other comprehensive income (loss)	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.17M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.41B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.10B	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$687.54M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$532.68M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$375.50M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$865.59M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$620.26M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$823.14M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$448.29M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$760.21M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$698.62M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$858.46M	USD	Point-in-time

Income Statement 44 line items

Line Item	Tag	Value	Unit	Period
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$82.47M	USD	3 Qtrs
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$64.37M	USD	3 Qtrs
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$15.20M	USD	1 Quarter
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$26.02M	USD	1 Quarter
Cost of sales	`CostOfGoodsAndServicesSold`	$393.00K	USD	1 Quarter
Cost of sales	`CostOfGoodsAndServicesSold`	$1.03M	USD	3 Qtrs
Cost of sales	`CostOfGoodsAndServicesSold`	$695.00K	USD	1 Quarter
Cost of sales	`CostOfGoodsAndServicesSold`	$695.00K	USD	3 Qtrs
Research and development	`ResearchAndDevelopmentExpense`	$247.51M	USD	3 Qtrs
Research and development	`ResearchAndDevelopmentExpense`	$82.56M	USD	1 Quarter
Research and development	`ResearchAndDevelopmentExpense`	$304.65M	USD	3 Qtrs
Research and development	`ResearchAndDevelopmentExpense`	$101.67M	USD	1 Quarter
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$31.10M	USD	1 Quarter
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$33.02M	USD	1 Quarter
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$97.20M	USD	3 Qtrs
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$82.29M	USD	3 Qtrs
Total cost and expenses	`OperatingExpenses`	$402.88M	USD	3 Qtrs
Total cost and expenses	`OperatingExpenses`	$330.50M	USD	3 Qtrs
Total cost and expenses	`OperatingExpenses`	$114.36M	USD	1 Quarter
Total cost and expenses	`OperatingExpenses`	$135.08M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-99.16M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-266.12M	USD	3 Qtrs
Loss from operations	`OperatingIncomeLoss`	$-109.06M	USD	1 Quarter
Loss from operations	`OperatingIncomeLoss`	$-320.40M	USD	3 Qtrs
Interest income	`InvestmentIncomeInterest`	$11.89M	USD	3 Qtrs
Interest income	`InvestmentIncomeInterest`	$4.50M	USD	1 Quarter
Interest income	`InvestmentIncomeInterest`	$2.89M	USD	1 Quarter
Interest income	`InvestmentIncomeInterest`	$11.28M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-309.12M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-90.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-93.08M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-94.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-254.23M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-106.17M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.75M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-109.87M	USD	1 Quarter
Net loss per share basic and diluted (in usd per share)	`EarningsPerShareBasicAndDiluted`	$-1.63	USD	1 Quarter
Net loss per share basic and diluted (in usd per share)	`EarningsPerShareBasicAndDiluted`	$-5.27	USD	3 Qtrs
Net loss per share basic and diluted (in usd per share)	`EarningsPerShareBasicAndDiluted`	$-1.81	USD	1 Quarter
Net loss per share basic and diluted (in usd per share)	`EarningsPerShareBasicAndDiluted`	$-4.45	USD	3 Qtrs
Weighted-average number of common shares used in computing net loss per share basic and diluted (in usd per share)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	58.80M	shares	1 Quarter
Weighted-average number of common shares used in computing net loss per share basic and diluted (in usd per share)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	58.66M	shares	3 Qtrs
Weighted-average number of common shares used in computing net loss per share basic and diluted (in usd per share)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	58.03M	shares	1 Quarter
Weighted-average number of common shares used in computing net loss per share basic and diluted (in usd per share)	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	57.16M	shares	3 Qtrs

Cash Flow Statement 71 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-309.12M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-90.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-93.08M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-94.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-254.23M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-106.17M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.75M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-109.87M	USD	1 Quarter
Depreciation	`Depreciation`	$5.26M	USD	3 Qtrs
Depreciation	`Depreciation`	$6.12M	USD	3 Qtrs
Stock-based compensation expense	`ShareBasedCompensation`	$55.17M	USD	3 Qtrs
Stock-based compensation expense	`ShareBasedCompensation`	$55.24M	USD	3 Qtrs
Net accretion of premium and discounts on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$2.54M	USD	3 Qtrs
Net accretion of premium and discounts on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$2.77M	USD	3 Qtrs
Loss (gain) on disposal of property and equipment	`GainLossOnDispositionOfAssets1`	$20.00K	USD	3 Qtrs
Loss (gain) on disposal of property and equipment	`GainLossOnDispositionOfAssets1`	$-466.00K	USD	3 Qtrs
Non-cash operating lease expense	`OperatingLeaseRightOfUseAssetAmortization`	$6.34M	USD	3 Qtrs
Accounts receivable, net	`IncreaseDecreaseInContractWithCustomerAsset`	$2.63M	USD	3 Qtrs
Accounts receivable, net	`IncreaseDecreaseInContractWithCustomerAsset`	$2.03M	USD	3 Qtrs
Collaboration receivable related party	`IncreaseDecreaseinCollaborationReceivableDuefromRelatedPartiesCurrent`	$-624.00K	USD	3 Qtrs
Collaboration receivable related party	`IncreaseDecreaseinCollaborationReceivableDuefromRelatedPartiesCurrent`	$947.00K	USD	3 Qtrs
Collaboration receivable other	`IncreaseDecreaseinCollaborationReceivableOtherCurrent`	$199.00K	USD	3 Qtrs
Collaboration receivable other	`IncreaseDecreaseinCollaborationReceivableOtherCurrent`	$440.00K	USD	3 Qtrs
Royalty receivable related party	`IncreaseDecreaseinRoyaltyReceivableDuefromRelatedPartiesCurrent`	$366.00K	USD	3 Qtrs
Royalty receivable related party	`IncreaseDecreaseinRoyaltyReceivableDuefromRelatedPartiesCurrent`	$641.00K	USD	3 Qtrs
Inventory	`IncreaseDecreaseInInventories`	$4.98M	USD	3 Qtrs
Inventory	`IncreaseDecreaseInInventories`	$863.00K	USD	3 Qtrs
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-1.71M	USD	3 Qtrs
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.55M	USD	3 Qtrs
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$2.65M	USD	3 Qtrs
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-5.83M	USD	3 Qtrs
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$4.60M	USD	3 Qtrs
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$-8.54M	USD	3 Qtrs
Deferred revenue related party	`IncreaseDecreaseInContractWithCustomerLiabilityRelatedParty`	$-15.75M	USD	3 Qtrs
Deferred revenue related party	`IncreaseDecreaseInContractWithCustomerLiabilityRelatedParty`	$-25.85M	USD	3 Qtrs
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-4.19M	USD	3 Qtrs
Deferred rent	`IncreaseDecreaseInDeferredCharges`	$-56.00K	USD	3 Qtrs
Deferred rent	`IncreaseDecreaseInDeferredCharges`	-	USD	3 Qtrs
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-277.01M	USD	3 Qtrs
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-230.23M	USD	3 Qtrs
Purchases of marketable securities	`PaymentsToAcquireMarketableSecurities`	$755.37M	USD	3 Qtrs
Purchases of marketable securities	`PaymentsToAcquireMarketableSecurities`	$194.82M	USD	3 Qtrs
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$476.38M	USD	3 Qtrs
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$500.28M	USD	3 Qtrs
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$5.35M	USD	3 Qtrs
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$5.93M	USD	3 Qtrs
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$276.21M	USD	3 Qtrs
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-261.02M	USD	3 Qtrs
Payment of public offering costs, net of reimbursements	`PaymentsOfStockIssuanceCosts`	$391.00K	USD	3 Qtrs
Payment of public offering costs, net of reimbursements	`PaymentsOfStockIssuanceCosts`	-	USD	3 Qtrs
Proceeds from public offering of common stock, net of commissions	`ProceedsFromIssuanceOfCommonStock`	-	USD	3 Qtrs
Proceeds from public offering of common stock, net of commissions	`ProceedsFromIssuanceOfCommonStock`	$516.21M	USD	3 Qtrs
Net proceeds from stock option exercises and employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$29.19M	USD	3 Qtrs
Net proceeds from stock option exercises and employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$12.01M	USD	3 Qtrs
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$545.01M	USD	3 Qtrs
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$12.01M	USD	3 Qtrs
Net change in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$53.75M	USD	3 Qtrs
Net change in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$11.21M	USD	3 Qtrs
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$81.71M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.72M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$70.50M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$156.48M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$81.71M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.72M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$70.50M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$156.48M	USD	Point-in-time
Additions to property and equipment in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$501.00K	USD	3 Qtrs
Additions to property and equipment in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$2.09M	USD	3 Qtrs
Proceeds from stock option exercises in other current assets	`ProceedsFromStockOptionsExercisedInOtherCurrentAssets`	-	USD	3 Qtrs
Proceeds from stock option exercises in other current assets	`ProceedsFromStockOptionsExercisedInOtherCurrentAssets`	$39.00K	USD	3 Qtrs
Operating lease liabilities arising from obtaining operating lease assets	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$42.32M	USD	3 Qtrs

Stockholders Equity 46 line items

Line Item	Tag	Value	Unit	Period
Beginning balance	`StockholdersEquity`	$687.54M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$532.68M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$375.50M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$865.59M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$620.26M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$823.14M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$448.29M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$760.21M	USD	Point-in-time
Issuance of common stock for follow-on offering	`StockIssuedDuringPeriodValueNewIssues`	$516.21M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	253,323.00	shares	3 Qtrs
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.23M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$9.64M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.77M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$12.33M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$7.26M	USD	1 Quarter
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$6.00M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$18.59M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$18.55M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$16.45M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$24.19M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$18.11M	USD	1 Quarter
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$14.52M	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$245.00K	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$-26.00K	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$974.00K	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$1.69M	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$279.00K	USD	1 Quarter
Other comprehensive income (loss)	`OtherComprehensiveIncomeLossNetOfTax`	$-1.25M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-309.12M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-90.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-93.08M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-94.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-254.23M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-106.17M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.75M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-109.87M	USD	1 Quarter
Other	`StockholdersEquityOther`	$-346.00K	USD	1 Quarter
Other	`StockholdersEquityOther`	$-45.00K	USD	1 Quarter
Ending balance	`StockholdersEquity`	$687.54M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$532.68M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$375.50M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$865.59M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$620.26M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$823.14M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$448.29M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$760.21M	USD	Point-in-time

Comprehensive Income 16 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-309.12M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-90.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-93.08M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-94.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-254.23M	USD	3 Qtrs
Net loss	`NetIncomeLoss`	$-106.17M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.75M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-109.87M	USD	1 Quarter
Unrealized (loss) gain on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$2.63M	USD	3 Qtrs
Unrealized (loss) gain on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$279.00K	USD	1 Quarter
Unrealized (loss) gain on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-26.00K	USD	1 Quarter
Unrealized (loss) gain on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-730.00K	USD	3 Qtrs
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-106.20M	USD	1 Quarter
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-306.49M	USD	3 Qtrs
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-94.39M	USD	1 Quarter
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-254.96M	USD	3 Qtrs

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.