10-K Filing

AGIOS PHARMACEUTICALS, INC. CIK: 1439222 FY 2023

Filing Information

Form Type	10-K
Accession Number	`0001439222-24-000035`
Period End Date	20231231
Filing Date	20240215
Fiscal Year	2023
Fiscal Period	FY
XBRL Instance	agio-20231231_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 74 Income Statement 63 Cash Flow Statement 125 Stockholders Equity 31 Comprehensive Income 9

Balance Sheet 74 line items

Line Item	Tag	Value	Unit	Period
Preferred stock, par value (in usd per share)	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, par value (in usd per share)	`PreferredStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Preferred stock, authorized (in shares)	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Preferred stock, authorized (in shares)	`PreferredStockSharesAuthorized`	25.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$139.26M	USD	Point-in-time
Preferred stock, issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$88.20M	USD	Point-in-time
Preferred stock, issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$688.72M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$643.86M	USD	Point-in-time
Preferred stock, outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Preferred stock, outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Common stock, par value (in usd per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Accounts receivable, net	`ContractWithCustomerAssetNetCurrent`	$2.21M	USD	Point-in-time
Common stock, par value (in usd per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Accounts receivable, net	`ContractWithCustomerAssetNetCurrent`	$2.81M	USD	Point-in-time
Common stock, authorized (in shares)	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Inventory	`InventoryNet`	$8.49M	USD	Point-in-time
Common stock, authorized (in shares)	`CommonStockSharesAuthorized`	125.00M	shares	Point-in-time
Inventory	`InventoryNet`	$19.08M	USD	Point-in-time
Common stock, issued (in shares)	`CommonStockSharesIssued`	71.26M	shares	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$38.95M	USD	Point-in-time
Common stock, issued (in shares)	`CommonStockSharesIssued`	72.16M	shares	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$35.02M	USD	Point-in-time
Common stock, outstanding (in shares)	`CommonStockSharesOutstanding`	55.04M	shares	Point-in-time
Common stock, outstanding (in shares)	`CommonStockSharesOutstanding`	55.95M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$833.84M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$832.77M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesNoncurrent`	$313.87M	USD	Point-in-time
Marketable securities	`AvailableForSaleSecuritiesDebtSecuritiesNoncurrent`	$29.43M	USD	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time
Operating lease assets	`OperatingLeaseRightOfUseAsset`	$65.13M	USD	Point-in-time
Operating lease assets	`OperatingLeaseRightOfUseAsset`	$54.41M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$22.99M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$15.38M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$4.06M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$3.96M	USD	Point-in-time
Total assets	`Assets`	$1.24B	USD	Point-in-time
Total assets	`Assets`	$937.12M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$9.78M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$18.62M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$43.17M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$30.35M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$13.66M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$15.01M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$62.63M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$67.95M	USD	Point-in-time
Operating lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$56.99M	USD	Point-in-time
Operating lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$72.00M	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$1.16M	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$3.28M	USD	Point-in-time
Total liabilities	`Liabilities`	$126.10M	USD	Point-in-time
Total liabilities	`Liabilities`	$137.90M	USD	Point-in-time
Commitments and contingent liabilities (Note 16)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingent liabilities (Note 16)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValueOutstanding`	-	USD	Point-in-time
Preferred stock, $0.001 par value; 25,000,000 shares authorized, no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValueOutstanding`	-	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized; 72,161,489 shares issued and 55,945,078 outstanding at December 31, 2023 and 71,256,118 shares issued and 55,039,707 outstanding at December 31, 2022	`CommonStockValueOutstanding`	$72.00K	USD	Point-in-time
Common stock, $0.001 par value; 125,000,000 shares authorized; 72,161,489 shares issued and 55,945,078 outstanding at December 31, 2023 and 71,256,118 shares issued and 55,039,707 outstanding at December 31, 2022	`CommonStockValueOutstanding`	$71.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.44B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.39B	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-12.54M	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-441.00K	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-470.56M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-822.65M	USD	Point-in-time
Treasury stock, at cost (16,216,411 shares at December 31, 2023 and December 31, 2022)	`TreasuryStockValue`	$802.49M	USD	Point-in-time
Treasury stock, at cost (16,216,411 shares at December 31, 2023 and December 31, 2022)	`TreasuryStockValue`	$802.49M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$1.29B	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$1.10B	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$399.50M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$811.02M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$937.12M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$1.24B	USD	Point-in-time

Income Statement 63 line items

Line Item	Tag	Value	Unit	Period
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$14.24M	USD	Annual
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	-	USD	Annual
Total revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$26.82M	USD	Annual
Cost of sales	`CostOfGoodsAndServicesSold`	-	USD	Annual
Cost of sales	`CostOfGoodsAndServicesSold`	$1.70M	USD	Annual
Cost of sales	`CostOfGoodsAndServicesSold`	$2.88M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$256.97M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$295.53M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$279.91M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$121.44M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$121.67M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$119.90M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$378.42M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$403.29M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$418.31M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-391.49M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-389.05M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-378.42M	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	-	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	$127.85M	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	-	USD	Annual
Royalty income from gain on sale of oncology business	`RoyaltyIncomeNonoperating`	-	USD	Annual
Royalty income from gain on sale of oncology business	`RoyaltyIncomeNonoperating`	$9.85M	USD	Annual
Royalty income from gain on sale of oncology business	`RoyaltyIncomeNonoperating`	$6.64M	USD	Annual
Interest income, net	`InterestIncomeExpenseNonoperatingNet`	$12.79M	USD	Annual
Interest income, net	`InterestIncomeExpenseNonoperatingNet`	$836.00K	USD	Annual
Interest income, net	`InterestIncomeExpenseNonoperatingNet`	$33.34M	USD	Annual
Other income, net	`OtherNonoperatingIncomeExpense`	$6.05M	USD	Annual
Other income, net	`OtherNonoperatingIncomeExpense`	$14.43M	USD	Annual
Other income, net	`OtherNonoperatingIncomeExpense`	$6.75M	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-231.80M	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-356.51M	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-352.09M	USD	Annual
Net income from discontinued operations, net of tax	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	$1.96B	USD	Annual
Net income from discontinued operations, net of tax	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	-	USD	Annual
Net income from discontinued operations, net of tax	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	-	USD	Annual
Net (loss) income	`NetIncomeLoss`	$1.60B	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-352.09M	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-231.80M	USD	Annual
Net loss from continuing operations per share - basic (in usd per share)	`IncomeLossFromContinuingOperationsPerBasicShare`	$-4.23	USD	Annual
Net loss from continuing operations per share - basic (in usd per share)	`IncomeLossFromContinuingOperationsPerBasicShare`	$-6.33	USD	Annual
Net loss from continuing operations per share - basic (in usd per share)	`IncomeLossFromContinuingOperationsPerBasicShare`	$-5.90	USD	Annual
Net loss from continuing operations per share - diluted (in usd per share)	`IncomeLossFromContinuingOperationsPerDilutedShare`	$-5.90	USD	Annual
Net loss from continuing operations per share - diluted (in usd per share)	`IncomeLossFromContinuingOperationsPerDilutedShare`	$-4.23	USD	Annual
Net loss from continuing operations per share - diluted (in usd per share)	`IncomeLossFromContinuingOperationsPerDilutedShare`	$-6.33	USD	Annual
Net income from discontinued operations per share - basic (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare`	$32.45	USD	Annual
Net income from discontinued operations per share - basic (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare`	-	USD	Annual
Net income from discontinued operations per share - basic (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerBasicShare`	-	USD	Annual
Net income from discontinued operations per share - diluted (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare`	$32.45	USD	Annual
Net income from discontinued operations per share - diluted (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare`	-	USD	Annual
Net income from discontinued operations per share - diluted (in usd per share)	`IncomeLossFromDiscontinuedOperationsNetOfTaxPerDilutedShare`	-	USD	Annual
Net (loss) income per share - basic (in usd per share)	`EarningsPerShareBasic`	$26.55	USD	Annual
Net (loss) income per share - basic (in usd per share)	`EarningsPerShareBasic`	$-4.23	USD	Annual
Net (loss) income per share - basic (in usd per share)	`EarningsPerShareBasic`	$-6.33	USD	Annual
Net (loss) income per share - diluted (in usd share)	`EarningsPerShareDiluted`	$-6.33	USD	Annual
Net (loss) income per share - diluted (in usd share)	`EarningsPerShareDiluted`	$-4.23	USD	Annual
Net (loss) income per share - diluted (in usd share)	`EarningsPerShareDiluted`	$26.55	USD	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	54.79M	shares	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	55.65M	shares	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	60.45M	shares	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	54.79M	shares	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	60.45M	shares	Annual
Weighted-average number of common shares used in computing net loss per share from continuing operations, net income per share from discontinued operations and net (loss) income per share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	55.65M	shares	Annual

Cash Flow Statement 125 line items

Line Item	Tag	Value	Unit	Period
Net (loss) income	`NetIncomeLoss`	$1.60B	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-352.09M	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-231.80M	USD	Annual
Less: Net income from discontinued operations	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	$1.96B	USD	Annual
Less: Net income from discontinued operations	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	-	USD	Annual
Less: Net income from discontinued operations	`IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity`	-	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperations`	$-231.80M	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperations`	$-356.51M	USD	Annual
Net loss from continuing operations	`IncomeLossFromContinuingOperations`	$-352.09M	USD	Annual
Depreciation and amortization	`OtherDepreciationAndAmortization`	$8.56M	USD	Annual
Depreciation and amortization	`OtherDepreciationAndAmortization`	$6.62M	USD	Annual
Depreciation and amortization	`OtherDepreciationAndAmortization`	$9.24M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$49.30M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$44.77M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$53.51M	USD	Annual
Net (accretion of discount) amortization of premium on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$5.05M	USD	Annual
Net (accretion of discount) amortization of premium on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$1.20M	USD	Annual
Net (accretion of discount) amortization of premium on marketable securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-6.95M	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	-	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	$127.85M	USD	Annual
Gain on sale of contingent payments	`GainLossOnSaleOfContingentPayments`	-	USD	Annual
Loss (gain) on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$48.00K	USD	Annual
Loss (gain) on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-12.00K	USD	Annual
Loss (gain) on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-553.00K	USD	Annual
Non-cash operating lease expense	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$10.72M	USD	Annual
Non-cash operating lease expense	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$9.99M	USD	Annual
Non-cash operating lease expense	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$9.54M	USD	Annual
Expense associated with license agreement	`ExpenseAssociatedWithLicenseAgreement`	$17.50M	USD	Annual
Expense associated with license agreement	`ExpenseAssociatedWithLicenseAgreement`	-	USD	Annual
Expense associated with license agreement	`ExpenseAssociatedWithLicenseAgreement`	-	USD	Annual
Realized gain on investments	`RealizedGainOnInvestments`	$28.00K	USD	Annual
Realized gain on investments	`RealizedGainOnInvestments`	-	USD	Annual
Realized gain on investments	`RealizedGainOnInvestments`	-	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	-	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$2.21M	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$604.00K	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	-	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$10.58M	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$8.49M	USD	Annual
Other receivables	`IncreaseDecreaseInContractWithCustomerAsset`	$4.38M	USD	Annual
Other receivables	`IncreaseDecreaseInContractWithCustomerAsset`	$-447.00K	USD	Annual
Other receivables	`IncreaseDecreaseInContractWithCustomerAsset`	-	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$26.85M	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$176.00K	USD	Annual
Prepaid expenses and other current and non-current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-3.83M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-8.73M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$1.86M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$3.44M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$-1.62M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$66.00K	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities`	$12.82M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-13.66M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-7.53M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-10.83M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	-	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$3.00M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-2.12M	USD	Annual
Net cash used in operating activities - continuing operations	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$-296.06M	USD	Annual
Net cash used in operating activities - continuing operations	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$-314.09M	USD	Annual
Net cash used in operating activities - continuing operations	`NetCashProvidedByUsedInOperatingActivitiesContinuingOperations`	$-309.48M	USD	Annual
Net cash used in operating activities - discontinued operations	`CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations`	-	USD	Annual
Net cash used in operating activities - discontinued operations	`CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations`	-	USD	Annual
Net cash used in operating activities - discontinued operations	`CashProvidedByUsedInOperatingActivitiesDiscontinuedOperations`	$-93.23M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-296.06M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-309.48M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-407.32M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$417.93M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$1.38B	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$1.03B	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$674.68M	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$1.15B	USD	Annual
Proceeds from maturities and sales of marketable securities	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$829.80M	USD	Annual
Proceeds from sale of contingent payments	`ProceedsFromSaleOfContingentPayments`	-	USD	Annual
Proceeds from sale of contingent payments	`ProceedsFromSaleOfContingentPayments`	-	USD	Annual
Proceeds from sale of contingent payments	`ProceedsFromSaleOfContingentPayments`	$131.78M	USD	Annual
Payments associated with license agreement	`PaymentsAssociatedWithLicenseAgreement`	-	USD	Annual
Payments associated with license agreement	`PaymentsAssociatedWithLicenseAgreement`	$17.50M	USD	Annual
Payments associated with license agreement	`PaymentsAssociatedWithLicenseAgreement`	-	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$4.88M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$999.00K	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$5.74M	USD	Annual
Proceeds from sale of equipment	`ProceedsFromSaleOfMachineryAndEquipment`	-	USD	Annual
Proceeds from sale of equipment	`ProceedsFromSaleOfMachineryAndEquipment`	$1.32M	USD	Annual
Proceeds from sale of equipment	`ProceedsFromSaleOfMachineryAndEquipment`	$964.00K	USD	Annual
Net cash provided by (used in) investing activities - continuing operations	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$-554.16M	USD	Annual
Net cash provided by (used in) investing activities - continuing operations	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$239.57M	USD	Annual
Net cash provided by (used in) investing activities - continuing operations	`NetCashProvidedByUsedInInvestingActivitiesContinuingOperations`	$243.26M	USD	Annual
Net cash provided by investing activities - discontinued operations	`CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations`	$1.80B	USD	Annual
Net cash provided by investing activities - discontinued operations	`CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations`	-	USD	Annual
Net cash provided by investing activities - discontinued operations	`CashProvidedByUsedInInvestingActivitiesDiscontinuedOperations`	-	USD	Annual
Net cash provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$243.26M	USD	Annual
Net cash provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$1.25B	USD	Annual
Net cash provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$239.57M	USD	Annual
Payments on financing lease obligations	`FinanceLeasePrincipalPayments`	-	USD	Annual
Payments on financing lease obligations	`FinanceLeasePrincipalPayments`	$331.00K	USD	Annual
Payments on financing lease obligations	`FinanceLeasePrincipalPayments`	$578.00K	USD	Annual
Purchase of treasury stock	`PaymentsForRepurchaseOfEquity`	$802.49M	USD	Annual
Purchase of treasury stock	`PaymentsForRepurchaseOfEquity`	-	USD	Annual
Purchase of treasury stock	`PaymentsForRepurchaseOfEquity`	-	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$5.43M	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$2.68M	USD	Annual
Net proceeds from stock option exercises and employee stock purchase plan	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$37.30M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-765.77M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$2.35M	USD	Annual
Net cash provided by (used in) financing activities	`NetCashProvidedByUsedInFinancingActivities`	$5.43M	USD	Annual
Net change in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$75.69M	USD	Annual
Net change in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-51.05M	USD	Annual
Net change in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-63.87M	USD	Annual
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$127.44M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$203.13M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$139.26M	USD	Point-in-time
Cash and cash equivalents at beginning of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$88.20M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$127.44M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$203.13M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$139.26M	USD	Point-in-time
Cash and cash equivalents at end of the period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$88.20M	USD	Point-in-time
Additions to property and equipment in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$1.68M	USD	Annual
Additions to property and equipment in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$158.00K	USD	Annual
Additions to property and equipment in accounts payable and accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$55.00K	USD	Annual
Net cash taxes paid	`IncomeTaxesPaid`	-	USD	Annual
Net cash taxes paid	`IncomeTaxesPaid`	$1.57M	USD	Annual
Net cash taxes paid	`IncomeTaxesPaid`	$16.08M	USD	Annual
Financing lease liabilities arising from obtaining financing lease assets	`RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability`	$511.00K	USD	Annual
Financing lease liabilities arising from obtaining financing lease assets	`RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability`	-	USD	Annual
Financing lease liabilities arising from obtaining financing lease assets	`RightOfUseAssetObtainedInExchangeForFinanceLeaseLiability`	-	USD	Annual

Stockholders Equity 31 line items

Line Item	Tag	Value	Unit	Period
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	55.04M	shares	Point-in-time
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	55.95M	shares	Point-in-time
Beginning balance	`StockholdersEquity`	$1.29B	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$1.10B	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$399.50M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$811.02M	USD	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesBeforeReclassificationAdjustmentsTax`	$11.34M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesBeforeReclassificationAdjustmentsTax`	$1.30M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesBeforeReclassificationAdjustmentsTax`	$-12.09M	USD	Annual
Net (loss) income	`NetIncomeLoss`	$1.60B	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-352.09M	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-231.80M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$53.51M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$44.77M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$49.30M	USD	Annual
Common stock issued under stock incentive plan and ESPP (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	235,401.00	shares	Annual
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$37.30M	USD	Annual
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$5.43M	USD	Annual
Common stock issued under stock incentive plan and ESPP	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.68M	USD	Annual
Repurchase of common stock	`TreasuryStockValueAcquiredCostMethod`	$802.49M	USD	Annual
Disposition of oncology business	`StockholdersEquityDispositionOfBusiness`	$-745.00K	USD	Annual
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	55.04M	shares	Point-in-time
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	55.95M	shares	Point-in-time
Ending balance	`StockholdersEquity`	$1.29B	USD	Point-in-time
Ending balance	`StockholdersEquity`	$1.10B	USD	Point-in-time
Ending balance	`StockholdersEquity`	$399.50M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$811.02M	USD	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	16.22M	shares	Point-in-time

Comprehensive Income 9 line items

Line Item	Tag	Value	Unit	Period
Net (loss) income	`NetIncomeLoss`	$1.60B	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-352.09M	USD	Annual
Net (loss) income	`NetIncomeLoss`	$-231.80M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-1.30M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-11.34M	USD	Annual
Unrealized gain (loss) on available-for-sale securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$12.09M	USD	Annual
Comprehensive (loss) income	`ComprehensiveIncomeNetOfTax`	$-243.14M	USD	Annual
Comprehensive (loss) income	`ComprehensiveIncomeNetOfTax`	$-339.99M	USD	Annual
Comprehensive (loss) income	`ComprehensiveIncomeNetOfTax`	$1.60B	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.