10-K Filing

TWIST BIOSCIENCE CORP CIK: 1581280 FY 2022

Filing Information

Form Type	10-K
Accession Number	`0001628280-22-030817`
Period End Date	20220930
Filing Date	20221128
Fiscal Year	2022
Fiscal Period	FY
XBRL Instance	twst-20220930_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 71 Income Statement 66 Cash Flow Statement 131 Stockholders Equity 40

Balance Sheet 71 line items

Line Item	Tag	Value	Unit	Period
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, share authorized (in shares)	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Common stock, share authorized (in shares)	`CommonStockSharesAuthorized`	100.00M	shares	Point-in-time
Common stock, share issued (in shares)	`CommonStockSharesIssued`	56.52M	shares	Point-in-time
Common stock, share issued (in shares)	`CommonStockSharesIssued`	49.50M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$465.83M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$378.69M	USD	Point-in-time
Common stock, outstanding (in shares)	`CommonStockSharesOutstanding`	56.52M	shares	Point-in-time
Common stock, outstanding (in shares)	`CommonStockSharesOutstanding`	49.50M	shares	Point-in-time
Short-term investments	`ShortTermInvestments`	$12.03M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$126.28M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$28.55M	USD	Point-in-time
Accounts receivable, net	`AccountsReceivableNetCurrent`	$40.29M	USD	Point-in-time
Inventories	`InventoryNet`	$31.80M	USD	Point-in-time
Inventories	`InventoryNet`	$39.31M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$11.91M	USD	Point-in-time
Prepaid expenses and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$8.28M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$596.48M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$546.50M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$44.12M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$139.44M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$74.95M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$61.58M	USD	Point-in-time
Goodwill	`Goodwill`	$1.14M	USD	Point-in-time
Goodwill	`Goodwill`	$85.81M	USD	Point-in-time
Goodwill	`Goodwill`	$22.43M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$59.74M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$18.26M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$1.53M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$1.57M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$7.67M	USD	Point-in-time
Other non-current assets	`OtherAssetsNoncurrent`	$3.38M	USD	Point-in-time
Total assets	`Assets`	$702.10M	USD	Point-in-time
Total assets	`Assets`	$961.38M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$14.90M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$20.09M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$10.17M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$6.44M	USD	Point-in-time
Accrued compensation	`EmployeeRelatedLiabilitiesCurrent`	$27.02M	USD	Point-in-time
Accrued compensation	`EmployeeRelatedLiabilitiesCurrent`	$22.33M	USD	Point-in-time
Current portion of operating lease liability	`OperatingLeaseLiabilityCurrent`	$13.64M	USD	Point-in-time
Current portion of operating lease liability	`OperatingLeaseLiabilityCurrent`	$8.21M	USD	Point-in-time
Current portion of long-term debt	`LongTermDebtCurrent`	-	USD	Point-in-time
Current portion of long-term debt	`LongTermDebtCurrent`	$1.55M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$9.62M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$19.74M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$63.05M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$90.66M	USD	Point-in-time
Operating lease liability, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$81.27M	USD	Point-in-time
Operating lease liability, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$53.16M	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$60.00K	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$5.07M	USD	Point-in-time
Total liabilities	`Liabilities`	$121.28M	USD	Point-in-time
Total liabilities	`Liabilities`	$171.99M	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.00001 par value 100,000 and 100,000 shares authorized at September 30, 2022 and 2021, respectively; 56,523 and 49,499 shares issued and outstanding at September 30, 2022 and 2021, respectively	`CommonStockValue`	-	USD	Point-in-time
Common stock, $0.00001 par value 100,000 and 100,000 shares authorized at September 30, 2022 and 2021, respectively; 56,523 and 49,499 shares issued and outstanding at September 30, 2022 and 2021, respectively	`CommonStockValue`	-	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$1.19B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$1.62B	USD	Point-in-time
Accumulated other comprehensive (loss)/income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$546.00K	USD	Point-in-time
Accumulated other comprehensive (loss)/income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-1.84M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-828.42M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-610.55M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$580.82M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$789.38M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$152.08M	USD	Point-in-time
Total stockholders equity	`StockholdersEquity`	$336.26M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$961.38M	USD	Point-in-time
Total liabilities and stockholders equity	`LiabilitiesAndStockholdersEquity`	$702.10M	USD	Point-in-time

Income Statement 66 line items

Line Item	Tag	Value	Unit	Period
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$90.10M	USD	Annual
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$203.56M	USD	Annual
Revenues	`RevenueFromContractWithCustomerIncludingAssessedTax`	$132.33M	USD	Annual
Cost of revenues	`CostOfRevenue`	$80.62M	USD	Annual
Cost of revenues	`CostOfRevenue`	$119.33M	USD	Annual
Cost of revenues	`CostOfRevenue`	$61.41M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$120.31M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$69.07M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$43.01M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$212.95M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$135.90M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$103.27M	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfContingentConsiderationAndIndemnityHoldback`	-	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfContingentConsiderationAndIndemnityHoldback`	$14.24M	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfContingentConsiderationAndIndemnityHoldback`	$534.00K	USD	Annual
Litigation settlement	`LitigationSettlementExpense`	-	USD	Annual
Litigation settlement	`LitigationSettlementExpense`	$22.50M	USD	Annual
Litigation settlement	`LitigationSettlementExpense`	-	USD	Annual
Total operating expenses	`CostsAndExpenses`	$230.18M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$285.06M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$438.34M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-152.73M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-234.78M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-140.08M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$435.00K	USD	Annual
Interest income	`InvestmentIncomeInterest`	$1.50M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$3.06M	USD	Annual
Interest expense	`InterestExpense`	$367.00K	USD	Annual
Interest expense	`InterestExpense`	$80.00K	USD	Annual
Interest expense	`InterestExpense`	$787.00K	USD	Annual
Gain on deconsolidation of subsidiary	`DeconsolidationGainOrLossAmount`	$4.61M	USD	Annual
Gain on deconsolidation of subsidiary	`DeconsolidationGainOrLossAmount`	-	USD	Annual
Gain on deconsolidation of subsidiary	`DeconsolidationGainOrLossAmount`	-	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-182.00K	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-1.09M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-1.37M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-154.03M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-228.27M	USD	Annual
Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-139.55M	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$-1.93M	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$-10.41M	USD	Annual
Benefit from (provision for) income taxes	`IncomeTaxExpenseBenefit`	$382.00K	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-152.10M	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-139.93M	USD	Annual
Net loss attributable to common stockholders	`NetIncomeLoss`	$-217.86M	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-1.59M	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-34.00K	USD	Annual
Change in unrealized gain (loss) on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-14.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-60.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-795.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$473.00K	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-220.25M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-151.64M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-140.03M	USD	Annual
Net loss per share attributable to common stockholdersbasic (in dollars per share)	`EarningsPerShareBasic`	$-4.04	USD	Annual
Net loss per share attributable to common stockholdersbasic (in dollars per share)	`EarningsPerShareBasic`	$-3.57	USD	Annual
Net loss per share attributable to common stockholdersbasic (in dollars per share)	`EarningsPerShareBasic`	$-3.15	USD	Annual
Net loss per share attributable to common stockholdersdiluted (in dollars per share)	`EarningsPerShareDiluted`	$-3.15	USD	Annual
Net loss per share attributable to common stockholdersdiluted (in dollars per share)	`EarningsPerShareDiluted`	$-4.04	USD	Annual
Net loss per share attributable to common stockholdersdiluted (in dollars per share)	`EarningsPerShareDiluted`	$-3.57	USD	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersbasic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	39.19M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersbasic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	53.88M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersbasic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	48.25M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersdiluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	53.88M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersdiluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	39.19M	shares	Annual
Weighted average shares used in computing net loss per share attributable to common stockholdersdiluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	48.25M	shares	Annual

Cash Flow Statement 131 line items

Line Item	Tag	Value	Unit	Period
Net loss	`ProfitLoss`	$-152.10M	USD	Annual
Net loss	`ProfitLoss`	$-139.93M	USD	Annual
Net loss	`ProfitLoss`	$-217.86M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$9.75M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$6.68M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$16.51M	USD	Annual
Non-cash lease expense, net of tenant improvement allowance	`OperatingLeaseImpairmentLoss`	$2.24M	USD	Annual
Non-cash lease expense, net of tenant improvement allowance	`OperatingLeaseImpairmentLoss`	$20.13M	USD	Annual
Non-cash lease expense, net of tenant improvement allowance	`OperatingLeaseImpairmentLoss`	$-1.04M	USD	Annual
Gain on deconsolidation of Revelar	`DeconsolidationGainOrLossAmount`	$4.61M	USD	Annual
Gain on deconsolidation of Revelar	`DeconsolidationGainOrLossAmount`	-	USD	Annual
Gain on deconsolidation of Revelar	`DeconsolidationGainOrLossAmount`	-	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	-	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	-	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-2.00K	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$79.66M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$17.10M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$37.00M	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-1.31M	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$214.00K	USD	Annual
Discount (premium) accretion on investment securities	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-593.00K	USD	Annual
Realized gain on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Realized gain on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Realized gain on investments	`RealizedInvestmentGainsLosses`	$5.00K	USD	Annual
Allowance for doubtful accounts	`ProvisionForDoubtfulAccounts`	$40.00K	USD	Annual
Allowance for doubtful accounts	`ProvisionForDoubtfulAccounts`	-	USD	Annual
Allowance for doubtful accounts	`ProvisionForDoubtfulAccounts`	$-11.00K	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfAcquisitionConsideration`	-	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfAcquisitionConsideration`	$-534.00K	USD	Annual
Change in fair value of contingent considerations and holdbacks	`ChangeInFairValueOfAcquisitionConsideration`	$-14.24M	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$152.00K	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$3.00K	USD	Annual
Non-cash interest expense	`OtherNoncashExpense`	$67.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$184.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$4.00K	USD	Annual
Amortization of debt discount	`AmortizationOfDebtDiscountPremium`	$81.00K	USD	Annual
Write off property and equipment	`PropertyPlantAndEquipmentWriteOff`	$70.00K	USD	Annual
Write off property and equipment	`PropertyPlantAndEquipmentWriteOff`	-	USD	Annual
Write off property and equipment	`PropertyPlantAndEquipmentWriteOff`	-	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$2.20M	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$14.27M	USD	Annual
Accounts receivable, net	`IncreaseDecreaseInAccountsReceivable`	$9.62M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$4.96M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$7.54M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$19.49M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.06M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.68M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.55M	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$4.65M	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$554.00K	USD	Annual
Other non-current assets	`IncreaseDecreaseInOtherNoncurrentAssets`	$-7.27M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$8.54M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$7.38M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-5.51M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$-2.65M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$2.27M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$3.12M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$4.85M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$7.39M	USD	Annual
Accrued compensation	`IncreaseDecreaseInEmployeeRelatedLiabilities`	$4.46M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$1.98M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-28.00K	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-7.42M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-124.39M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-142.25M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-112.24M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$9.87M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$27.06M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$101.86M	USD	Annual
Business acquisition, net of cash acquired	`PaymentsToAcquireBusinessesNetOfCashAcquired`	-	USD	Annual
Business acquisition, net of cash acquired	`PaymentsToAcquireBusinessesNetOfCashAcquired`	$8.16M	USD	Annual
Business acquisition, net of cash acquired	`PaymentsToAcquireBusinessesNetOfCashAcquired`	$483.00K	USD	Annual
Deconsolidation of cash and cash equivalent relating to Revelar	`CashDivestedFromDeconsolidation`	-	USD	Annual
Deconsolidation of cash and cash equivalent relating to Revelar	`CashDivestedFromDeconsolidation`	-	USD	Annual
Deconsolidation of cash and cash equivalent relating to Revelar	`CashDivestedFromDeconsolidation`	$5.75M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$202.88M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$217.64M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$58.80M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$98.10M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$100.48M	USD	Annual
Proceeds from maturity of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$242.49M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-232.93M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-114.65M	USD	Annual
Net cash provided by (used in) investing activities	`NetCashProvidedByUsedInInvestingActivities`	$156.16M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$14.56M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$10.49M	USD	Annual
Proceeds from exercise of stock options	`ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions`	$6.01M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$269.82M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$295.56M	USD	Annual
Proceeds from public offerings, net of underwriting discounts, commissions and offering expenses	`ProceedsFromIssuanceInitialPublicOffering`	$323.86M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$4.01M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$3.43M	USD	Annual
Proceeds from issuance under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$4.94M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$1.56M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$3.33M	USD	Annual
Repayments of long-term debt	`RepaymentsOfLongTermDebt`	$3.33M	USD	Annual
Repurchases of common stock for income tax withholding	`PaymentsToRepurchasesOfCommonStockForTaxWithholding`	$2.42M	USD	Annual
Repurchases of common stock for income tax withholding	`PaymentsToRepurchasesOfCommonStockForTaxWithholding`	$10.85M	USD	Annual
Repurchases of common stock for income tax withholding	`PaymentsToRepurchasesOfCommonStockForTaxWithholding`	$7.75M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$303.73M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$329.18M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$270.53M	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$20.00K	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$21.00K	USD	Annual
Effect of exchange rates on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-319.00K	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-87.10M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$46.85M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$373.11M	USD	Annual
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$94.25M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$467.36M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$47.40M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at beginning of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$380.26M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$94.25M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$467.36M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$47.40M	USD	Point-in-time
Cash, cash equivalents, and restricted cash at end of year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$380.26M	USD	Point-in-time
Interest paid	`InterestPaidNet`	$167.00K	USD	Annual
Interest paid	`InterestPaidNet`	$9.00K	USD	Annual
Interest paid	`InterestPaidNet`	$438.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$172.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$101.00K	USD	Annual
Income taxes paid, net of refunds	`IncomeTaxesPaidNet`	$246.00K	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$2.01M	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$1.33M	USD	Annual
Property and equipment additions included in accrued expenses and accounts payable	`LiabilitiesAssumed1`	$6.30M	USD	Annual
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$33.62M	USD	Annual
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$3.72M	USD	Annual
Operating lease right-of-use assets obtained in exchange for operating lease liabilities	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$21.37M	USD	Annual
Issuance of common stock in connection with the business acquisition	`StockIssued1`	-	USD	Annual
Issuance of common stock in connection with the business acquisition	`StockIssued1`	$26.77M	USD	Annual
Issuance of common stock in connection with the business acquisition	`StockIssued1`	$77.12M	USD	Annual

Stockholders Equity 40 line items

Line Item	Tag	Value	Unit	Period
Net of underwriting discounts, commissions and offering expenses	`AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts`	$17.68M	USD	Annual
Net of underwriting discounts, commissions and offering expenses	`AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts`	$18.92M	USD	Annual
Net of underwriting discounts, commissions and offering expenses	`AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts`	$21.14M	USD	Annual
Beginning balance (in shares)	`CommonStockSharesOutstanding`	56.52M	shares	Point-in-time
Beginning balance (in shares)	`CommonStockSharesOutstanding`	49.50M	shares	Point-in-time
Beginning balance	`StockholdersEquity`	$580.82M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$789.38M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$152.08M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$336.26M	USD	Point-in-time
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$269.82M	USD	Annual
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$323.86M	USD	Annual
Issuance of common stock in public offerings, net of underwriting discounts, commissions and offering expenses	`StockIssuedDuringPeriodValueNewIssues`	$295.56M	USD	Annual
Issuance of shares under the employee stock purchase plan (in shares)	`StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans`	97,000.00	shares	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$3.43M	USD	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$4.94M	USD	Annual
Issuance of shares under the employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$4.01M	USD	Annual
Exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	484,000.00	shares	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$10.54M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$5.95M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$14.47M	USD	Annual
Business acquisition	`StockIssuedDuringPeriodValueAcquisitions`	$26.77M	USD	Annual
Business acquisition	`StockIssuedDuringPeriodValueAcquisitions`	$77.12M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$17.10M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$37.00M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$79.66M	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-94.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$459.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncomeLossNetOfTax`	$-2.39M	USD	Annual
Repurchase of common stock for income tax withholdings	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$10.85M	USD	Annual
Repurchase of common stock for income tax withholdings	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$2.42M	USD	Annual
Repurchase of common stock for income tax withholdings	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$7.75M	USD	Annual
Net loss	`ProfitLoss`	$-152.10M	USD	Annual
Net loss	`ProfitLoss`	$-139.93M	USD	Annual
Net loss	`ProfitLoss`	$-217.86M	USD	Annual
Ending balance (in shares)	`CommonStockSharesOutstanding`	56.52M	shares	Point-in-time
Ending balance (in shares)	`CommonStockSharesOutstanding`	49.50M	shares	Point-in-time
Ending balance	`StockholdersEquity`	$580.82M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$789.38M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$152.08M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$336.26M	USD	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.