20-F Filing

ADC Therapeutics SA CIK: 1771910 FY 2022

Filing Information

Form Type	20-F
Accession Number	`0001628280-23-008056`
Period End Date	20221231
Filing Date	20230315
Fiscal Year	2022
Fiscal Period	FY
XBRL Instance	adc-20221231_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 72 Income Statement 51 Cash Flow Statement 149 Stockholders Equity 48 Comprehensive Income 24

Balance Sheet 72 line items

Line Item	Tag	Value	Unit	Period
Cash and cash equivalents	`CashAndCashEquivalents`	$466.54M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalents`	$115.55M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalents`	$439.19M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalents`	$326.44M	USD	Point-in-time
Accounts receivable, net	`TradeAndOtherCurrentReceivables`	$30.22M	USD	Point-in-time
Accounts receivable, net	`TradeAndOtherCurrentReceivables`	$72.97M	USD	Point-in-time
Inventory	`Inventories`	$18.56M	USD	Point-in-time
Inventory	`Inventories`	$11.12M	USD	Point-in-time
Other current assets	`OtherCurrentAssets`	$28.04M	USD	Point-in-time
Other current assets	`OtherCurrentAssets`	$17.30M	USD	Point-in-time
Total current assets	`CurrentAssets`	$525.18M	USD	Point-in-time
Total current assets	`CurrentAssets`	$446.01M	USD	Point-in-time
Property, plant and equipment	`PropertyPlantAndEquipment`	$4.07M	USD	Point-in-time
Property, plant and equipment	`PropertyPlantAndEquipment`	$3.26M	USD	Point-in-time
Right-of-use assets	`RightofuseAssets`	$6.72M	USD	Point-in-time
Right-of-use assets	`RightofuseAssets`	$7.16M	USD	Point-in-time
Intangible assets	`IntangibleAssetsOtherThanGoodwill`	$14.36M	USD	Point-in-time
Intangible assets	`IntangibleAssetsOtherThanGoodwill`	$13.58M	USD	Point-in-time
Interest in joint venture	`InvestmentsInJointVenturesAccountedForUsingEquityMethod`	$31.15M	USD	Point-in-time
Interest in joint venture	`InvestmentsInJointVenturesAccountedForUsingEquityMethod`	$41.24M	USD	Point-in-time
Deferred tax asset	`NetDeferredTaxAssets`	$26.05M	USD	Point-in-time
Deferred tax asset	`NetDeferredTaxAssets`	$26.76M	USD	Point-in-time
Other long-term assets	`OtherNoncurrentAssets`	$693.00K	USD	Point-in-time
Other long-term assets	`OtherNoncurrentAssets`	$903.00K	USD	Point-in-time
Total non-current assets	`NoncurrentAssets`	$83.15M	USD	Point-in-time
Total non-current assets	`NoncurrentAssets`	$92.79M	USD	Point-in-time
Total assets	`Assets`	$617.97M	USD	Point-in-time
Total assets	`Assets`	$529.17M	USD	Point-in-time
Accounts payable	`TradeAndOtherCurrentPayables`	$12.08M	USD	Point-in-time
Accounts payable	`TradeAndOtherCurrentPayables`	$12.35M	USD	Point-in-time
Other current liabilities	`CurrentAccruedExpensesAndOtherCurrentLiabilities`	$50.50M	USD	Point-in-time
Other current liabilities	`CurrentAccruedExpensesAndOtherCurrentLiabilities`	$73.03M	USD	Point-in-time
Lease liabilities, short-term	`CurrentLeaseLiabilities`	$1.10M	USD	Point-in-time
Lease liabilities, short-term	`CurrentLeaseLiabilities`	$1.03M	USD	Point-in-time
Current income tax payable	`CurrentTaxLiabilitiesCurrent`	$3.75M	USD	Point-in-time
Current income tax payable	`CurrentTaxLiabilitiesCurrent`	-	USD	Point-in-time
Total current liabilities	`CurrentLiabilities`	$73.94M	USD	Point-in-time
Total current liabilities	`CurrentLiabilities`	$98.96M	USD	Point-in-time
Convertible loans, derivatives	`NoncurrentDerivativeFinancialLiabilities`	$37.95M	USD	Point-in-time
Convertible loans, derivatives	`NoncurrentDerivativeFinancialLiabilities`	-	USD	Point-in-time
Warrant obligations	`WarrantyLiabilityNoncurrent`	-	USD	Point-in-time
Warrant obligations	`WarrantyLiabilityNoncurrent`	$1.79M	USD	Point-in-time
Deferred royalty obligation, long-term	`DeferredRoyaltyObligationNoncurrent`	$218.66M	USD	Point-in-time
Deferred royalty obligation, long-term	`DeferredRoyaltyObligationNoncurrent`	$212.35M	USD	Point-in-time
Deferred gain of joint venture	`ContingentLiabilitiesIncurredByVenturerInRelationToInterestsInJointVentures`	$23.54M	USD	Point-in-time
Deferred gain of joint venture	`ContingentLiabilitiesIncurredByVenturerInRelationToInterestsInJointVentures`	$23.54M	USD	Point-in-time
Lease liabilities, long-term	`NoncurrentLeaseLiabilities`	$6.99M	USD	Point-in-time
Lease liabilities, long-term	`NoncurrentLeaseLiabilities`	$6.56M	USD	Point-in-time
Defined benefit pension liabilities	`NoncurrentRecognisedLiabilitiesDefinedBenefitPlan`	$3.65M	USD	Point-in-time
Defined benefit pension liabilities	`NoncurrentRecognisedLiabilitiesDefinedBenefitPlan`	-	USD	Point-in-time
Total non-current liabilities	`NoncurrentLiabilities`	$377.95M	USD	Point-in-time
Total non-current liabilities	`NoncurrentLiabilities`	$341.48M	USD	Point-in-time
Total liabilities	`Liabilities`	$451.88M	USD	Point-in-time
Total liabilities	`Liabilities`	$440.44M	USD	Point-in-time
Share capital	`IssuedCapital`	$7.31M	USD	Point-in-time
Share capital	`IssuedCapital`	$6.45M	USD	Point-in-time
Share premium	`SharePremium`	$1.01B	USD	Point-in-time
Share premium	`SharePremium`	$981.83M	USD	Point-in-time
Treasury shares	`TreasuryShares`	$679.00K	USD	Point-in-time
Treasury shares	`TreasuryShares`	$128.00K	USD	Point-in-time
Other reserves	`OtherReserves`	$155.68M	USD	Point-in-time
Other reserves	`OtherReserves`	$102.65M	USD	Point-in-time
Cumulative translation adjustments	`ReserveOfExchangeDifferencesOnTranslation`	$183.00K	USD	Point-in-time
Cumulative translation adjustments	`ReserveOfExchangeDifferencesOnTranslation`	$-356.00K	USD	Point-in-time
Cumulative translation adjustments	`RetainedEarnings`	$-924.88M	USD	Point-in-time
Cumulative translation adjustments	`RetainedEarnings`	$-1.08B	USD	Point-in-time
Total equity attributable to owners of the parent	`Equity`	$111.16M	USD	Point-in-time
Total equity attributable to owners of the parent	`Equity`	$335.50M	USD	Point-in-time
Total equity attributable to owners of the parent	`Equity`	$166.09M	USD	Point-in-time
Total equity attributable to owners of the parent	`Equity`	$88.73M	USD	Point-in-time
Total liabilities and equity	`EquityAndLiabilities`	$529.17M	USD	Point-in-time
Total liabilities and equity	`EquityAndLiabilities`	$617.97M	USD	Point-in-time

Income Statement 51 line items

Line Item	Tag	Value	Unit	Period
Total revenue	`RevenueFromContractsWithCustomers`	$209.91M	USD	Annual
Total revenue	`RevenueFromContractsWithCustomers`	$33.92M	USD	Annual
Total revenue	`RevenueFromContractsWithCustomers`	-	USD	Annual
Cost of product sales	`CostOfSales`	-	USD	Annual
Cost of product sales	`CostOfSales`	$1.39M	USD	Annual
Cost of product sales	`CostOfSales`	$4.58M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$187.90M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$142.03M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$158.00M	USD	Annual
Selling and marketing expenses	`SalesAndMarketingExpense`	$22.10M	USD	Annual
Selling and marketing expenses	`SalesAndMarketingExpense`	$64.78M	USD	Annual
Selling and marketing expenses	`SalesAndMarketingExpense`	$69.05M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$55.13M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$72.01M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$71.46M	USD	Annual
Total operating expense	`OperatingExpense`	$333.54M	USD	Annual
Total operating expense	`OperatingExpense`	$219.26M	USD	Annual
Total operating expense	`OperatingExpense`	$295.64M	USD	Annual
Loss from operations	`ProfitLossFromOperatingActivities`	$-261.72M	USD	Annual
Loss from operations	`ProfitLossFromOperatingActivities`	$-219.26M	USD	Annual
Loss from operations	`ProfitLossFromOperatingActivities`	$-123.63M	USD	Annual
Financial income	`FinanceIncome`	$832.00K	USD	Annual
Financial income	`FinanceIncome`	$17.97M	USD	Annual
Financial income	`FinanceIncome`	$66.00K	USD	Annual
Financial expense	`FinanceCosts`	$18.34M	USD	Annual
Financial expense	`FinanceCosts`	$36.92M	USD	Annual
Financial expense	`FinanceCosts`	$4.93M	USD	Annual
Non-operating (expense) income	`NonOperatingIncomeExpense`	$28.49M	USD	Annual
Non-operating (expense) income	`NonOperatingIncomeExpense`	$-12.08M	USD	Annual
Non-operating (expense) income	`NonOperatingIncomeExpense`	$-22.61M	USD	Annual
Total other (expense) income	`OtherNonOperatingIncomeExpense`	$10.21M	USD	Annual
Total other (expense) income	`OtherNonOperatingIncomeExpense`	$-31.03M	USD	Annual
Total other (expense) income	`OtherNonOperatingIncomeExpense`	$-26.70M	USD	Annual
Loss before taxes	`ProfitLossBeforeTax`	$-251.50M	USD	Annual
Loss before taxes	`ProfitLossBeforeTax`	$-154.66M	USD	Annual
Loss before taxes	`ProfitLossBeforeTax`	$-245.96M	USD	Annual
Income tax (expense) benefit	`IncomeTaxExpenseContinuingOperations`	$1.14M	USD	Annual
Income tax (expense) benefit	`IncomeTaxExpenseContinuingOperations`	$327.00K	USD	Annual
Income tax (expense) benefit	`IncomeTaxExpenseContinuingOperations`	$-21.48M	USD	Annual
Net loss	`ProfitLoss`	$-246.29M	USD	Annual
Net loss	`ProfitLoss`	$-155.80M	USD	Annual
Net loss	`ProfitLoss`	$-230.03M	USD	Annual
Owners of the parent	`ProfitLossAttributableToOwnersOfParent`	$-155.80M	USD	Annual
Owners of the parent	`ProfitLossAttributableToOwnersOfParent`	$-246.29M	USD	Annual
Owners of the parent	`ProfitLossAttributableToOwnersOfParent`	$-230.03M	USD	Annual
Basic net loss per share (in USD per share)	`BasicEarningsLossPerShareFromContinuingOperations`	$-3.77	USD	Annual
Basic net loss per share (in USD per share)	`BasicEarningsLossPerShareFromContinuingOperations`	$-3.00	USD	Annual
Basic net loss per share (in USD per share)	`BasicEarningsLossPerShareFromContinuingOperations`	$-1.99	USD	Annual
Diluted net loss per share (in USD per share)	`DilutedEarningsLossPerShareFromDiscontinuedOperations`	$-1.99	USD	Annual
Diluted net loss per share (in USD per share)	`DilutedEarningsLossPerShareFromDiscontinuedOperations`	$-3.00	USD	Annual
Diluted net loss per share (in USD per share)	`DilutedEarningsLossPerShareFromDiscontinuedOperations`	$-3.77	USD	Annual

Cash Flow Statement 149 line items

Line Item	Tag	Value	Unit	Period
Loss for the year	`ProfitLoss`	$-246.29M	USD	Annual
Loss for the year	`ProfitLoss`	$-155.80M	USD	Annual
Loss for the year	`ProfitLoss`	$-230.03M	USD	Annual
Share-based compensation expense	`AdjustmentsForSharebasedPayments`	$60.48M	USD	Annual
Share-based compensation expense	`AdjustmentsForSharebasedPayments`	$49.32M	USD	Annual
Share-based compensation expense	`AdjustmentsForSharebasedPayments`	$37.59M	USD	Annual
Impairment of Assets	`ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss`	-	USD	Annual
Impairment of Assets	`ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss`	-	USD	Annual
Impairment of Assets	`ImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLoss`	$2.70M	USD	Annual
Depreciation of property, plant and equipment	`AdjustmentsForDepreciationExpensePropertyPlantAndEquipment`	$1.02M	USD	Annual
Depreciation of property, plant and equipment	`AdjustmentsForDepreciationExpensePropertyPlantAndEquipment`	$774.00K	USD	Annual
Depreciation of property, plant and equipment	`AdjustmentsForDepreciationExpensePropertyPlantAndEquipment`	$920.00K	USD	Annual
Amortization of intangible assets	`AdjustmentsForAmortisationExpense`	$47.00K	USD	Annual
Amortization of intangible assets	`AdjustmentsForAmortisationExpense`	$129.00K	USD	Annual
Amortization of intangible assets	`AdjustmentsForAmortisationExpense`	$118.00K	USD	Annual
Depreciation of right-of-use assets	`AdjustmentsForDepreciationExpenseOfRightOfUseAssets`	$1.19M	USD	Annual
Depreciation of right-of-use assets	`AdjustmentsForDepreciationExpenseOfRightOfUseAssets`	$1.58M	USD	Annual
Depreciation of right-of-use assets	`AdjustmentsForDepreciationExpenseOfRightOfUseAssets`	$1.15M	USD	Annual
Gain from reversal of inventory impairment charges	`AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossInventories`	$-8.10M	USD	Annual
Gain from reversal of inventory impairment charges	`AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossInventories`	-	USD	Annual
Gain from reversal of inventory impairment charges	`AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossInventories`	-	USD	Annual
Share of results in joint venture	`ShareOfProfitLossOfJointVenturesAccountedForUsingEquityMethod`	$-10.08M	USD	Annual
Share of results in joint venture	`ShareOfProfitLossOfJointVenturesAccountedForUsingEquityMethod`	$-6.67M	USD	Annual
Share of results in joint venture	`ShareOfProfitLossOfJointVenturesAccountedForUsingEquityMethod`	$24.37M	USD	Annual
Deferred income taxes	`IncreaseDecreaseInDeferredTaxLiabilityAsset`	$26.05M	USD	Annual
Deferred income taxes	`IncreaseDecreaseInDeferredTaxLiabilityAsset`	-	USD	Annual
Deferred income taxes	`IncreaseDecreaseInDeferredTaxLiabilityAsset`	$708.00K	USD	Annual
Convertible loans, derivatives, (decrease) increase in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives`	$-45.41M	USD	Annual
Convertible loans, derivatives, (decrease) increase in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives`	$25.65M	USD	Annual
Convertible loans, derivatives, (decrease) increase in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfDerivatives`	$34.89M	USD	Annual
Change in defined benefit pension liability	`AdjustmentsForIncreaseDecreaseInNonCurrentNetDefinedBenefitLiability`	$108.00K	USD	Annual
Change in defined benefit pension liability	`AdjustmentsForIncreaseDecreaseInNonCurrentNetDefinedBenefitLiability`	$276.00K	USD	Annual
Change in defined benefit pension liability	`AdjustmentsForIncreaseDecreaseInNonCurrentNetDefinedBenefitLiability`	$-365.00K	USD	Annual
Warrant obligations, decrease in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfWarrants`	-	USD	Annual
Warrant obligations, decrease in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfWarrants`	$14.47M	USD	Annual
Warrant obligations, decrease in fair value	`AdjustmentsForGainsLossesOnChangeInFairValueOfWarrants`	-	USD	Annual
Impairment of intangible assets	`ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill`	-	USD	Annual
Impairment of intangible assets	`ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill`	$226.00K	USD	Annual
Impairment of intangible assets	`ImpairmentLossRecognisedInProfitOrLossIntangibleAssetsOtherThanGoodwill`	$216.00K	USD	Annual
Financial income	`AdjustmentsForFinanceIncome`	$66.00K	USD	Annual
Financial income	`AdjustmentsForFinanceIncome`	$17.97M	USD	Annual
Financial income	`AdjustmentsForFinanceIncome`	$832.00K	USD	Annual
Financial expense	`AdjustmentsForFinanceCosts`	$18.12M	USD	Annual
Financial expense	`AdjustmentsForFinanceCosts`	$36.73M	USD	Annual
Financial expense	`AdjustmentsForFinanceCosts`	$4.82M	USD	Annual
Loss on extinguishment	`GainsLossOnExtinguishmentOfBorrowings`	-	USD	Annual
Loss on extinguishment	`GainsLossOnExtinguishmentOfBorrowings`	$-42.11M	USD	Annual
Loss on extinguishment	`GainsLossOnExtinguishmentOfBorrowings`	-	USD	Annual
Exchange differences	`AdjustmentsForUnrealisedForeignExchangeLossesGains`	$-185.00K	USD	Annual
Exchange differences	`AdjustmentsForUnrealisedForeignExchangeLossesGains`	$476.00K	USD	Annual
Exchange differences	`AdjustmentsForUnrealisedForeignExchangeLossesGains`	$-107.00K	USD	Annual
Operating loss before working capital changes	`CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital`	$-71.08M	USD	Annual
Operating loss before working capital changes	`CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital`	$-180.73M	USD	Annual
Operating loss before working capital changes	`CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital`	$-211.78M	USD	Annual
Increase in accounts receivable, net	`AdjustmentsForDecreaseIncreaseInTradeAccountReceivable`	$-42.75M	USD	Annual
Increase in accounts receivable, net	`AdjustmentsForDecreaseIncreaseInTradeAccountReceivable`	$-30.22M	USD	Annual
Increase in accounts receivable, net	`AdjustmentsForDecreaseIncreaseInTradeAccountReceivable`	-	USD	Annual
Increase in inventory	`AdjustmentsForDecreaseIncreaseInInventories`	$-3.02M	USD	Annual
Increase in inventory	`AdjustmentsForDecreaseIncreaseInInventories`	$-8.96M	USD	Annual
Increase in inventory	`AdjustmentsForDecreaseIncreaseInInventories`	-	USD	Annual
Increase in other current assets	`AdjustmentsForDecreaseIncreaseInOtherCurrentAssets`	$-4.50M	USD	Annual
Increase in other current assets	`AdjustmentsForDecreaseIncreaseInOtherCurrentAssets`	$-3.55M	USD	Annual
Increase in other current assets	`AdjustmentsForDecreaseIncreaseInOtherCurrentAssets`	$-6.36M	USD	Annual
Increase in trade accounts payable	`AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables`	$310.00K	USD	Annual
Increase in trade accounts payable	`AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables`	$6.80M	USD	Annual
Increase in trade accounts payable	`AdjustmentsForIncreaseDecreaseInTradeAndOtherPayables`	$1.92M	USD	Annual
Increase in income taxes	`AdjustmentsForIncomeTaxExpense`	$1.85M	USD	Annual
Increase in income taxes	`AdjustmentsForIncomeTaxExpense`	$4.57M	USD	Annual
Increase in income taxes	`AdjustmentsForIncomeTaxExpense`	$327.00K	USD	Annual
Increase in other liabilities and other payables	`AdjustmentsForIncreaseDecreaseInOtherLiabilities`	$20.10M	USD	Annual
Increase in other liabilities and other payables	`AdjustmentsForIncreaseDecreaseInOtherLiabilities`	$12.52M	USD	Annual
Increase in other liabilities and other payables	`AdjustmentsForIncreaseDecreaseInOtherLiabilities`	$14.95M	USD	Annual
Cash used in operating activities	`CashFlowsFromUsedInOperations`	$-168.04M	USD	Annual
Cash used in operating activities	`CashFlowsFromUsedInOperations`	$-227.50M	USD	Annual
Cash used in operating activities	`CashFlowsFromUsedInOperations`	$-104.09M	USD	Annual
Interest received	`InterestReceivedClassifiedAsOperatingActivities`	$56.00K	USD	Annual
Interest received	`InterestReceivedClassifiedAsOperatingActivities`	$1.95M	USD	Annual
Interest received	`InterestReceivedClassifiedAsOperatingActivities`	$797.00K	USD	Annual
Interest paid	`InterestPaidClassifiedAsOperatingActivities`	$5.28M	USD	Annual
Interest paid	`InterestPaidClassifiedAsOperatingActivities`	$10.37M	USD	Annual
Interest paid	`InterestPaidClassifiedAsOperatingActivities`	$1.56M	USD	Annual
Interest expense on lease obligations	`InterestExpenseOnLeaseLiabilities`	$225.00K	USD	Annual
Interest expense on lease obligations	`InterestExpenseOnLeaseLiabilities`	$105.00K	USD	Annual
Interest expense on lease obligations	`InterestExpenseOnLeaseLiabilities`	$191.00K	USD	Annual
Payments made under royalty financing transaction	`PaymentsMadeUnderRoyaltyFinancingTransactions`	$11.00M	USD	Annual
Payments made under royalty financing transaction	`PaymentsMadeUnderRoyaltyFinancingTransactions`	-	USD	Annual
Payments made under royalty financing transaction	`PaymentsMadeUnderRoyaltyFinancingTransactions`	$213.00K	USD	Annual
Tax paid	`IncomeTaxesPaidRefundClassifiedAsOperatingActivities`	$671.00K	USD	Annual
Tax paid	`IncomeTaxesPaidRefundClassifiedAsOperatingActivities`	$29.00K	USD	Annual
Tax paid	`IncomeTaxesPaidRefundClassifiedAsOperatingActivities`	$13.47M	USD	Annual
Net cash used in operating activities	`CashFlowsFromUsedInOperatingActivities`	$-136.79M	USD	Annual
Net cash used in operating activities	`CashFlowsFromUsedInOperatingActivities`	$-233.38M	USD	Annual
Net cash used in operating activities	`CashFlowsFromUsedInOperatingActivities`	$-168.73M	USD	Annual
Payment for purchases of property, plant and equipment	`PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities`	$577.00K	USD	Annual
Payment for purchases of property, plant and equipment	`PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities`	$3.43M	USD	Annual
Payment for purchases of property, plant and equipment	`PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities`	$801.00K	USD	Annual
Payment for purchases of intangible assets	`PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities`	$2.01M	USD	Annual
Payment for purchases of intangible assets	`PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities`	$1.72M	USD	Annual
Payment for purchases of intangible assets	`PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities`	$2.95M	USD	Annual
Payment for deposits	`PaymentForRentDeposits`	$19.00K	USD	Annual
Payment for deposits	`PaymentForRentDeposits`	$297.00K	USD	Annual
Payment for deposits	`PaymentForRentDeposits`	$210.00K	USD	Annual
Net cash used in investing activities	`CashFlowsFromUsedInInvestingActivities`	$-2.51M	USD	Annual
Net cash used in investing activities	`CashFlowsFromUsedInInvestingActivities`	$-6.67M	USD	Annual
Net cash used in investing activities	`CashFlowsFromUsedInInvestingActivities`	$-2.83M	USD	Annual
Proceeds from senior secured term loans, net of transaction costs	`ProceedsFromCapitalContributionsNetOfTransactionCosts`	-	USD	Annual
Proceeds from senior secured term loans, net of transaction costs	`ProceedsFromCapitalContributionsNetOfTransactionCosts`	$112.81M	USD	Annual
Proceeds from senior secured term loans, net of transaction costs	`ProceedsFromCapitalContributionsNetOfTransactionCosts`	-	USD	Annual
Convertible loans exchange	`ConvertibleLoansExchange`	$118.30M	USD	Annual
Convertible loans exchange	`ConvertibleLoansExchange`	-	USD	Annual
Convertible loans exchange	`ConvertibleLoansExchange`	-	USD	Annual
Share capital increases, transaction costs	`ShareCapitalTransactionCosts`	$221.00K	USD	Annual
Share capital increases, transaction costs	`ShareCapitalTransactionCosts`	-	USD	Annual
Share capital increases, transaction costs	`ShareCapitalTransactionCosts`	-	USD	Annual
Proceeds from convertible loans, net of transaction costs	`ProceedsFromBorrowingsClassifiedAsFinancingActivities`	$49.59M	USD	Annual
Proceeds from convertible loans, net of transaction costs	`ProceedsFromBorrowingsClassifiedAsFinancingActivities`	$62.90M	USD	Annual
Proceeds from convertible loans, net of transaction costs	`ProceedsFromBorrowingsClassifiedAsFinancingActivities`	-	USD	Annual
Proceeds from deferred royalty transaction, net of transaction costs	`ProceedsFromDeferredRoyaltyTransactionNet`	-	USD	Annual
Proceeds from deferred royalty transaction, net of transaction costs	`ProceedsFromDeferredRoyaltyTransactionNet`	-	USD	Annual
Proceeds from deferred royalty transaction, net of transaction costs	`ProceedsFromDeferredRoyaltyTransactionNet`	$218.00M	USD	Annual
Proceeds from the exercise of stock options	`ProceedsFromExerciseOfOptions`	$54.00K	USD	Annual
Proceeds from the exercise of stock options	`ProceedsFromExerciseOfOptions`	-	USD	Annual
Proceeds from the exercise of stock options	`ProceedsFromExerciseOfOptions`	$778.00K	USD	Annual
Principal portion of lease obligations payments	`PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities`	$1.14M	USD	Annual
Principal portion of lease obligations payments	`PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities`	$1.01M	USD	Annual
Principal portion of lease obligations payments	`PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities`	$977.00K	USD	Annual
Net cash (used in) provided by financing activities	`CashFlowsFromUsedInFinancingActivities`	$494.97M	USD	Annual
Net cash (used in) provided by financing activities	`CashFlowsFromUsedInFinancingActivities`	$-593.00K	USD	Annual
Net cash (used in) provided by financing activities	`CashFlowsFromUsedInFinancingActivities`	$267.39M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges`	$27.34M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges`	$-139.90M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges`	$323.41M	USD	Annual
Exchange (losses)/gains on cash and cash equivalents	`EffectOfExchangeRateChangesOnCashAndCashEquivalents`	$6.00K	USD	Annual
Exchange (losses)/gains on cash and cash equivalents	`EffectOfExchangeRateChangesOnCashAndCashEquivalents`	$-208.00K	USD	Annual
Exchange (losses)/gains on cash and cash equivalents	`EffectOfExchangeRateChangesOnCashAndCashEquivalents`	$235.00K	USD	Annual
Cash and cash equivalents at beginning of year	`CashAndCashEquivalents`	$466.54M	USD	Point-in-time
Cash and cash equivalents at beginning of year	`CashAndCashEquivalents`	$115.55M	USD	Point-in-time
Cash and cash equivalents at beginning of year	`CashAndCashEquivalents`	$439.19M	USD	Point-in-time
Cash and cash equivalents at beginning of year	`CashAndCashEquivalents`	$326.44M	USD	Point-in-time
Cash and cash equivalents at end of year	`CashAndCashEquivalents`	$439.19M	USD	Point-in-time
Cash and cash equivalents at end of year	`CashAndCashEquivalents`	$466.54M	USD	Point-in-time
Cash and cash equivalents at end of year	`CashAndCashEquivalents`	$115.55M	USD	Point-in-time
Cash and cash equivalents at end of year	`CashAndCashEquivalents`	$326.44M	USD	Point-in-time
Issuance of shares, Deerfield exchange agreement	`IssuanceOfShares`	-	USD	Annual
Issuance of shares, Deerfield exchange agreement	`IssuanceOfShares`	-	USD	Annual
Issuance of shares, Deerfield exchange agreement	`IssuanceOfShares`	$19.84M	USD	Annual
Capital expenditures and intangible asset acquisitions recorded in Accounts payable and Other current liabilities	`CapitalExpendituresIncurredButNotYetPaid`	$220.00K	USD	Annual
Capital expenditures and intangible asset acquisitions recorded in Accounts payable and Other current liabilities	`CapitalExpendituresIncurredButNotYetPaid`	-	USD	Annual
Capital expenditures and intangible asset acquisitions recorded in Accounts payable and Other current liabilities	`CapitalExpendituresIncurredButNotYetPaid`	$593.00K	USD	Annual

Stockholders Equity 48 line items

Line Item	Tag	Value	Unit	Period
Equity, beginning balance	`Equity`	$111.16M	USD	Point-in-time
Equity, beginning balance	`Equity`	$335.50M	USD	Point-in-time
Equity, beginning balance	`Equity`	$166.09M	USD	Point-in-time
Equity, beginning balance	`Equity`	$88.73M	USD	Point-in-time
Total comprehensive loss	`ComprehensiveIncome`	$-246.42M	USD	Annual
Total comprehensive loss	`ComprehensiveIncome`	$-152.62M	USD	Annual
Total comprehensive loss	`ComprehensiveIncome`	$-230.68M	USD	Annual
Net loss	`ProfitLoss`	$-246.29M	USD	Annual
Net loss	`ProfitLoss`	$-155.80M	USD	Annual
Net loss	`ProfitLoss`	$-230.03M	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$3.18M	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$-649.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$-129.00K	USD	Annual
Translation adjustment	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$-62.00K	USD	Annual
Translation adjustment	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$176.00K	USD	Annual
Translation adjustment	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$-539.00K	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$-305.00K	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$-587.00K	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$3.71M	USD	Annual
Total transactions with owners	`IncreaseDecreaseThroughTransactionsWithOwners`	$75.26M	USD	Annual
Total transactions with owners	`IncreaseDecreaseThroughTransactionsWithOwners`	$61.26M	USD	Annual
Total transactions with owners	`IncreaseDecreaseThroughTransactionsWithOwners`	$470.77M	USD	Annual
Share issue related cost	`ShareIssueRelatedCost`	$31.00K	USD	Annual
Shares surrendered to redeem share purchase plan promissory notes	`IncreaseDecreaseThroughSharesSurrenderedToRedeemSharePurchasePlanPromissoryNotes`	-	USD	Annual
Issuance of shares through capitalization of reserves	`IssueOfEquityThroughCapitalizationOfReserves`	-	USD	Annual
Issuance of shares to be held as treasury shares	`IncreaseDecreaseThroughTreasuryShareTransactions`	-	USD	Annual
Issuance of shares to be held as treasury shares	`IncreaseDecreaseThroughTreasuryShareTransactions`	-	USD	Annual
Issuance of shares to be held as treasury shares	`IncreaseDecreaseThroughTreasuryShareTransactions`	$254.00K	USD	Point-in-time
Issuance of shares to be held as treasury shares	`IncreaseDecreaseThroughTreasuryShareTransactions`	$131.00K	USD	Point-in-time
Issuance of shares to be held as treasury shares	`IncreaseDecreaseThroughTreasuryShareTransactions`	-	USD	Annual
Grant of shares to settle 2014 incentive plan awards	`IncreaseDecreaseThroughIssuanceToSettleIncentivePlanAwards`	-	USD	Annual
Issuance of shares at initial public offering	`IssueOfEquityThroughInitialPublicOffering`	$232.67M	USD	Annual
Sale of shares under greenshoe option	`IssueOfEquityThroughOverAllotmentOption`	$34.90M	USD	Annual
Transaction costs, initial public offering and greenshoe option	`ShareIssueRelatedCostThroughInitialPublicOfferingAndOverAllotmentOption`	$23.36M	USD	Annual
Issuance of shares at follow-on offering	`IssueOfEquityThroughFollowOnOffering`	$204.00M	USD	Annual
Transaction costs, follow-on offering	`ShareIssueRelatedCostThroughFollowOnOffering`	$15.08M	USD	Annual
Exercise of options	`IncreaseDecreaseThroughExerciseOfOptions`	$54.00K	USD	Annual
Exercise of options	`IncreaseDecreaseThroughExerciseOfOptions`	-	USD	Annual
Exercise of options	`IncreaseDecreaseThroughExerciseOfOptions`	$778.00K	USD	Annual
Share-based compensation expense	`IncreaseDecreaseThroughSharebasedPaymentTransactions`	$49.32M	USD	Annual
Share-based compensation expense	`IncreaseDecreaseThroughSharebasedPaymentTransactions`	$37.59M	USD	Annual
Share-based compensation expense	`IncreaseDecreaseThroughSharebasedPaymentTransactions`	$60.48M	USD	Annual
Equity, ending balance	`Equity`	$111.16M	USD	Point-in-time
Equity, ending balance	`Equity`	$335.50M	USD	Point-in-time
Equity, ending balance	`Equity`	$166.09M	USD	Point-in-time
Equity, ending balance	`Equity`	$88.73M	USD	Point-in-time
Issue Of Equity Through Exchange Agreement	`IssueOfEquityThroughExchangeAgreement`	$19.83M	USD	Annual
Issue Of Equity Through Purchase Agreement	`IssueOfEquityThroughPurchaseAgreement`	$6.13M	USD	Annual

Comprehensive Income 24 line items

Line Item	Tag	Value	Unit	Period
Net loss	`ProfitLoss`	$-246.29M	USD	Annual
Net loss	`ProfitLoss`	$-155.80M	USD	Annual
Net loss	`ProfitLoss`	$-230.03M	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$-305.00K	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$-587.00K	USD	Annual
Remeasurements of defined benefit plan	`OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans`	$3.71M	USD	Annual
Total items that will not be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax`	$-587.00K	USD	Annual
Total items that will not be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax`	$3.71M	USD	Annual
Total items that will not be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillNotBeReclassifiedToProfitOrLossNetOfTax`	$-305.00K	USD	Annual
Currency translation differences	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$176.00K	USD	Annual
Currency translation differences	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$-539.00K	USD	Annual
Currency translation differences	`OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation`	$-62.00K	USD	Annual
Total items that may be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax`	$-539.00K	USD	Annual
Total items that may be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax`	$176.00K	USD	Annual
Total items that may be reclassified to profit or loss	`OtherComprehensiveIncomeThatWillBeReclassifiedToProfitOrLossNetOfTax`	$-62.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$-129.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$-649.00K	USD	Annual
Other comprehensive loss	`OtherComprehensiveIncome`	$3.18M	USD	Annual
Total comprehensive loss	`ComprehensiveIncome`	$-246.42M	USD	Annual
Total comprehensive loss	`ComprehensiveIncome`	$-152.62M	USD	Annual
Total comprehensive loss	`ComprehensiveIncome`	$-230.68M	USD	Annual
Owners of the parent	`ComprehensiveIncomeAttributableToOwnersOfParent`	$-246.42M	USD	Annual
Owners of the parent	`ComprehensiveIncomeAttributableToOwnersOfParent`	$-152.62M	USD	Annual
Owners of the parent	`ComprehensiveIncomeAttributableToOwnersOfParent`	$-230.68M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.