10-K Filing

ZAI LAB LTD CIK: 1704292 FY 2023

Filing Information

Form Type	10-K
Accession Number	`0001628280-24-007235`
Period End Date	20231231
Filing Date	20240227
Fiscal Year	2023
Fiscal Period	FY
XBRL Instance	zlab-20231231_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 82 Income Statement 57 Cash Flow Statement 162 Stockholders Equity 39 Comprehensive Income 12

Balance Sheet 82 line items

Line Item	Tag	Value	Unit	Period
Accounts receivable, allowance for credit loss	`AllowanceForDoubtfulAccountsReceivableCurrent`	$11.00K	USD	Point-in-time
Accounts receivable, allowance for credit loss	`AllowanceForDoubtfulAccountsReceivableCurrent`	$17.00K	USD	Point-in-time
Ordinary shares, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Ordinary shares, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Ordinary shares, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Ordinary shares, shares authorized (in shares)	`CommonStockSharesAuthorized`	5.00B	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$964.10M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$1.01B	USD	Point-in-time
Ordinary shares, shares authorized (in shares)	`CommonStockSharesAuthorized`	5.00B	shares	Point-in-time
Ordinary shares, shares authorized (in shares)	`CommonStockSharesAuthorized`	5.00B	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$790.15M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$16.30M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	-	USD	Point-in-time
Ordinary shares, shares issued (in shares)	`CommonStockSharesIssued`	962.46M	shares	Point-in-time
Ordinary shares, shares issued (in shares)	`CommonStockSharesIssued`	977.15M	shares	Point-in-time
Ordinary shares, shares outstanding (in shares)	`CommonStockSharesOutstanding`	960.22M	shares	Point-in-time
Accounts receivable (net of allowance for credit loss of $17 and $11 as of December 31, 2023 and 2022, respectively)	`AccountsReceivableNetCurrent`	$59.20M	USD	Point-in-time
Ordinary shares, shares outstanding (in shares)	`CommonStockSharesOutstanding`	972.24M	shares	Point-in-time
Accounts receivable (net of allowance for credit loss of $17 and $11 as of December 31, 2023 and 2022, respectively)	`AccountsReceivableNetCurrent`	$39.96M	USD	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	4.91M	shares	Point-in-time
Notes receivable	`FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLossCurrent`	$8.61M	USD	Point-in-time
Notes receivable	`FinancingReceivableExcludingAccruedInterestAfterAllowanceForCreditLossCurrent`	$6.13M	USD	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	2.24M	shares	Point-in-time
Inventories, net	`InventoryNet`	$31.62M	USD	Point-in-time
Inventories, net	`InventoryNet`	$44.83M	USD	Point-in-time
Prepayments and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$23.00M	USD	Point-in-time
Prepayments and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$35.67M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$939.61M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$1.12B	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$1.11M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$803.00K	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$803.00K	USD	Point-in-time
Long-term investments	`LongTermInvestments`	$9.22M	USD	Point-in-time
Long-term investments	`LongTermInvestments`	$6.43M	USD	Point-in-time
Prepayments for equipment	`PrepaymentsForEquipment`	$111.00K	USD	Point-in-time
Prepayments for equipment	`PrepaymentsForEquipment`	$1.40M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$53.73M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$57.86M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$19.51M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$14.84M	USD	Point-in-time
Land use rights, net	`LandUseRightsNetNoncurrent`	$3.07M	USD	Point-in-time
Land use rights, net	`LandUseRightsNetNoncurrent`	$6.89M	USD	Point-in-time
Intangible assets, net	`IntangibleAssetsNetExcludingGoodwill`	$13.39M	USD	Point-in-time
Intangible assets, net	`IntangibleAssetsNetExcludingGoodwill`	$1.51M	USD	Point-in-time
Long-term deposits	`DepositsAssetsNoncurrent`	$1.40M	USD	Point-in-time
Long-term deposits	`DepositsAssetsNoncurrent`	$1.21M	USD	Point-in-time
Total assets	`Assets`	$1.22B	USD	Point-in-time
Total assets	`Assets`	$1.04B	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$112.99M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$65.97M	USD	Point-in-time
Current operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.05M	USD	Point-in-time
Current operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.10M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$82.97M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$66.82M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$203.07M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$139.84M	USD	Point-in-time
Deferred income	`DeferredIncomeNoncurrent`	$21.36M	USD	Point-in-time
Deferred income	`DeferredIncomeNoncurrent`	$28.74M	USD	Point-in-time
Non-current operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$8.05M	USD	Point-in-time
Non-current operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$13.34M	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	-	USD	Point-in-time
Other non-current liabilities	`OtherLiabilitiesNoncurrent`	$325.00K	USD	Point-in-time
Total liabilities	`Liabilities`	$174.54M	USD	Point-in-time
Total liabilities	`Liabilities`	$240.18M	USD	Point-in-time
Commitments and contingencies (Note 20)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 20)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Ordinary shares (par value of $0.000006 per share; 5,000,000,000 shares authorized, 977,151,270 and 962,455,850 shares issued as of December 31, 2023 and 2022, respectively; 972,239,070 and 960,219,570 shares issued and outstanding as of December 31, 2023 and 2022, respectively)	`CommonStockValue`	$6.00K	USD	Point-in-time
Ordinary shares (par value of $0.000006 per share; 5,000,000,000 shares authorized, 977,151,270 and 962,455,850 shares issued as of December 31, 2023 and 2022, respectively; 972,239,070 and 960,219,570 shares issued and outstanding as of December 31, 2023 and 2022, respectively)	`CommonStockValue`	$6.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.98B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.89B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.86B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-2.20B	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$25.68M	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$37.63M	USD	Point-in-time
Treasury stock (at cost, 4,912,200 and 2,236,280 shares as of December 31, 2023 and 2022, respectively)	`TreasuryStockCommonValue`	$11.86M	USD	Point-in-time
Treasury stock (at cost, 4,912,200 and 2,236,280 shares as of December 31, 2023 and 2022, respectively)	`TreasuryStockCommonValue`	$20.84M	USD	Point-in-time
Total shareholders equity	`StockholdersEquity`	$1.38B	USD	Point-in-time
Total shareholders equity	`StockholdersEquity`	$1.05B	USD	Point-in-time
Total shareholders equity	`StockholdersEquity`	$796.12M	USD	Point-in-time
Total shareholders equity	`StockholdersEquity`	$1.17B	USD	Point-in-time
Total liabilities and shareholders equity	`LiabilitiesAndStockholdersEquity`	$1.04B	USD	Point-in-time
Total liabilities and shareholders equity	`LiabilitiesAndStockholdersEquity`	$1.22B	USD	Point-in-time

Income Statement 57 line items

Line Item	Tag	Value	Unit	Period
Product revenue, net	`RevenueFromContractWithCustomerExcludingAssessedTax`	$266.72M	USD	Annual
Product revenue, net	`RevenueFromContractWithCustomerExcludingAssessedTax`	$212.67M	USD	Annual
Product revenue, net	`RevenueFromContractWithCustomerExcludingAssessedTax`	$144.10M	USD	Annual
Collaboration revenue	`RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer`	$207.00K	USD	Annual
Collaboration revenue	`RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer`	-	USD	Annual
Collaboration revenue	`RevenueFromCollaborativeArrangementExcludingRevenueFromContractWithCustomer`	$2.37M	USD	Annual
Total revenues	`Revenues`	$266.72M	USD	Annual
Total revenues	`Revenues`	$144.31M	USD	Annual
Total revenues	`Revenues`	$215.04M	USD	Annual
Cost of sales	`CostOfRevenue`	$74.02M	USD	Annual
Cost of sales	`CostOfRevenue`	$52.24M	USD	Annual
Cost of sales	`CostOfRevenue`	$95.82M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$286.41M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$265.87M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$573.31M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$218.83M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$281.61M	USD	Annual
Selling, general and administrative	`SellingGeneralAndAdministrativeExpense`	$258.97M	USD	Annual
Gain on sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	-	USD	Annual
Gain on sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	$10.00M	USD	Annual
Gain on sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	-	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-700.06M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-404.36M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-366.57M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$14.58M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$2.19M	USD	Annual
Interest income	`InvestmentIncomeInterest`	$39.80M	USD	Annual
Foreign currency (loss) gain	`ForeignCurrencyTransactionGainLossBeforeTax`	$-56.40M	USD	Annual
Foreign currency (loss) gain	`ForeignCurrencyTransactionGainLossBeforeTax`	$-14.85M	USD	Annual
Foreign currency (loss) gain	`ForeignCurrencyTransactionGainLossBeforeTax`	$4.66M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$3.11M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$7.01M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-10.20M	USD	Annual
Loss before income tax and share of loss from equity method investment	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments`	$-443.06M	USD	Annual
Loss before income tax and share of loss from equity method investment	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments`	$-334.62M	USD	Annual
Loss before income tax and share of loss from equity method investment	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments`	$-703.41M	USD	Annual
Income tax expense	`IncomeTaxExpenseBenefit`	-	USD	Annual
Income tax expense	`IncomeTaxExpenseBenefit`	-	USD	Annual
Income tax expense	`IncomeTaxExpenseBenefit`	-	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	$-1.06M	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	$-221.00K	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	-	USD	Annual
Net loss	`NetIncomeLoss`	$-334.62M	USD	Annual
Net loss	`NetIncomeLoss`	$-704.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-443.29M	USD	Annual
Loss per share basic (in dollars per share)	`EarningsPerShareBasic`	$-0.35	USD	Annual
Loss per share basic (in dollars per share)	`EarningsPerShareBasic`	$-0.76	USD	Annual
Loss per share basic (in dollars per share)	`EarningsPerShareBasic`	$-0.46	USD	Annual
Loss per share diluted (in dollars per share)	`EarningsPerShareDiluted`	$-0.76	USD	Annual
Loss per share diluted (in dollars per share)	`EarningsPerShareDiluted`	$-0.46	USD	Annual
Loss per share diluted (in dollars per share)	`EarningsPerShareDiluted`	$-0.35	USD	Annual
Weighted-average shares used in calculating net loss per ordinary share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	966.39M	shares	Annual
Weighted-average shares used in calculating net loss per ordinary share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	929.92M	shares	Annual
Weighted-average shares used in calculating net loss per ordinary share basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	958.07M	shares	Annual
Weighted-average shares used in calculating net loss per ordinary share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	958.07M	shares	Annual
Weighted-average shares used in calculating net loss per ordinary share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	966.39M	shares	Annual
Weighted-average shares used in calculating net loss per ordinary share diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	929.92M	shares	Annual

Cash Flow Statement 162 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-334.62M	USD	Annual
Net loss	`NetIncomeLoss`	$-704.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-443.29M	USD	Annual
Allowance for credit loss	`ProvisionForDoubtfulAccounts`	$10.00K	USD	Annual
Allowance for credit loss	`ProvisionForDoubtfulAccounts`	$6.00K	USD	Annual
Allowance for credit loss	`ProvisionForDoubtfulAccounts`	$1.00K	USD	Annual
Inventory write-down	`InventoryWriteDown`	$1.37M	USD	Annual
Inventory write-down	`InventoryWriteDown`	$973.00K	USD	Annual
Inventory write-down	`InventoryWriteDown`	$477.00K	USD	Annual
Depreciation and amortization expenses	`DepreciationDepletionAndAmortization`	$9.03M	USD	Annual
Depreciation and amortization expenses	`DepreciationDepletionAndAmortization`	$8.23M	USD	Annual
Depreciation and amortization expenses	`DepreciationDepletionAndAmortization`	$6.49M	USD	Annual
Impairment of property and equipment	`TangibleAssetImpairmentCharges`	-	USD	Annual
Impairment of property and equipment	`TangibleAssetImpairmentCharges`	$57.00K	USD	Annual
Impairment of property and equipment	`TangibleAssetImpairmentCharges`	-	USD	Annual
Amortization of deferred income	`AmortizationOfDeferredIncome`	$-3.38M	USD	Annual
Amortization of deferred income	`AmortizationOfDeferredIncome`	$-521.00K	USD	Annual
Amortization of deferred income	`AmortizationOfDeferredIncome`	$-2.60M	USD	Annual
Share-based compensation	`ShareBasedCompensation`	$79.63M	USD	Annual
Share-based compensation	`ShareBasedCompensation`	$61.30M	USD	Annual
Share-based compensation	`ShareBasedCompensation`	$40.71M	USD	Annual
Noncash research and development expenses	`NoncashResearchAndDevelopmentExpenses`	-	USD	Annual
Noncash research and development expenses	`NoncashResearchAndDevelopmentExpenses`	$62.25M	USD	Annual
Noncash research and development expenses	`NoncashResearchAndDevelopmentExpenses`	-	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	$-1.06M	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	$-221.00K	USD	Annual
Share of loss from equity method investment	`IncomeLossFromEquityMethodInvestments`	-	USD	Annual
(Gain) loss from fair value changes of equity investment with readily determinable fair value	`EquitySecuritiesFvNiGainLoss`	$-8.95M	USD	Annual
(Gain) loss from fair value changes of equity investment with readily determinable fair value	`EquitySecuritiesFvNiGainLoss`	$-14.62M	USD	Annual
(Gain) loss from fair value changes of equity investment with readily determinable fair value	`EquitySecuritiesFvNiGainLoss`	$2.79M	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-560.00K	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-29.00K	USD	Annual
Loss on disposal of property and equipment	`GainLossOnSaleOfPropertyPlantEquipment`	$-159.00K	USD	Annual
Gain on disposal of land use right	`GainLossOnDisposalOfLandUseRights`	$408.00K	USD	Annual
Gain on disposal of land use right	`GainLossOnDisposalOfLandUseRights`	-	USD	Annual
Gain on disposal of land use right	`GainLossOnDisposalOfLandUseRights`	-	USD	Annual
Noncash lease expenses	`NonCashLeaseExpenses`	$8.71M	USD	Annual
Noncash lease expenses	`NonCashLeaseExpenses`	$6.12M	USD	Annual
Noncash lease expenses	`NonCashLeaseExpenses`	$8.35M	USD	Annual
Gain from sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	-	USD	Annual
Gain from sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	$10.00M	USD	Annual
Gain from sale of intellectual property	`GainLossOnDispositionOfIntangibleAssets`	-	USD	Annual
Foreign currency remeasurement loss (gain)	`ForeignCurrencyTransactionGainLossUnrealized`	$-14.85M	USD	Annual
Foreign currency remeasurement loss (gain)	`ForeignCurrencyTransactionGainLossUnrealized`	$10.68M	USD	Annual
Foreign currency remeasurement loss (gain)	`ForeignCurrencyTransactionGainLossUnrealized`	$-56.40M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-4.33M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$42.32M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$20.04M	USD	Annual
Notes receivable	`IncreaseDecreaseInNotesReceivableCurrent`	$-2.35M	USD	Annual
Notes receivable	`IncreaseDecreaseInNotesReceivableCurrent`	$1.98M	USD	Annual
Notes receivable	`IncreaseDecreaseInNotesReceivableCurrent`	$7.33M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$7.17M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$14.91M	USD	Annual
Inventories	`IncreaseDecreaseInInventories`	$15.38M	USD	Annual
Prepayments and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$7.09M	USD	Annual
Prepayments and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-12.25M	USD	Annual
Prepayments and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$19.26M	USD	Annual
Long-term deposits	`IncreaseDecreaseInLongTermDeposits`	$527.00K	USD	Annual
Long-term deposits	`IncreaseDecreaseInLongTermDeposits`	$8.00K	USD	Annual
Long-term deposits	`IncreaseDecreaseInLongTermDeposits`	$-187.00K	USD	Annual
Value added tax recoverable	`IncreaseDecreaseInValueAddedTaxesReceivable`	$1.72M	USD	Annual
Value added tax recoverable	`IncreaseDecreaseInValueAddedTaxesReceivable`	$-22.78M	USD	Annual
Value added tax recoverable	`IncreaseDecreaseInValueAddedTaxesReceivable`	-	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-53.77M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$36.80M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$63.52M	USD	Annual
Other current liabilities	`IncreaseDecreaseInOtherCurrentLiabilities`	$19.81M	USD	Annual
Other current liabilities	`IncreaseDecreaseInOtherCurrentLiabilities`	$30.14M	USD	Annual
Other current liabilities	`IncreaseDecreaseInOtherCurrentLiabilities`	$7.39M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-8.35M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-8.46M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiabilities`	$-5.38M	USD	Annual
Deferred income	`IncreaseDecreaseInDeferredRevenue`	$11.18M	USD	Annual
Deferred income	`IncreaseDecreaseInDeferredRevenue`	$-1.38M	USD	Annual
Deferred income	`IncreaseDecreaseInDeferredRevenue`	$11.15M	USD	Annual
Other non-current Liabilities	`IncreaseDecreaseInOtherNoncurrentLiabilities`	-	USD	Annual
Other non-current Liabilities	`IncreaseDecreaseInOtherNoncurrentLiabilities`	-	USD	Annual
Other non-current Liabilities	`IncreaseDecreaseInOtherNoncurrentLiabilities`	$325.00K	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-198.18M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-549.23M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-367.64M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireShortTermInvestments`	$260.27M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireShortTermInvestments`	$134.00M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireShortTermInvestments`	$445.00M	USD	Annual
Proceeds from maturity of short-term investments	`ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments`	$705.27M	USD	Annual
Proceeds from maturity of short-term investments	`ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments`	$743.90M	USD	Annual
Proceeds from maturity of short-term investments	`ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments`	$117.70M	USD	Annual
Purchase of investment in equity investee	`PaymentsToAcquireEquityMethodInvestments`	-	USD	Annual
Purchase of investment in equity investee	`PaymentsToAcquireEquityMethodInvestments`	$30.00M	USD	Annual
Purchase of investment in equity investee	`PaymentsToAcquireEquityMethodInvestments`	-	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$7.21M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$18.30M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$24.59M	USD	Annual
Proceeds from the sale of property and equipment	`ProceedsFromSaleOfPropertyPlantAndEquipment`	$3.00K	USD	Annual
Proceeds from the sale of property and equipment	`ProceedsFromSaleOfPropertyPlantAndEquipment`	$122.00K	USD	Annual
Proceeds from the sale of property and equipment	`ProceedsFromSaleOfPropertyPlantAndEquipment`	-	USD	Annual
Acquisition of intangible assets	`PaymentsToAcquireIntangibleAssets`	$399.00K	USD	Annual
Acquisition of intangible assets	`PaymentsToAcquireIntangibleAssets`	$1.28M	USD	Annual
Acquisition of intangible assets	`PaymentsToAcquireIntangibleAssets`	$653.00K	USD	Annual
Proceeds from sale of intellectual property	`ProceedsFromSaleOfIntangibleAssets`	-	USD	Annual
Proceeds from sale of intellectual property	`ProceedsFromSaleOfIntangibleAssets`	-	USD	Annual
Proceeds from sale of intellectual property	`ProceedsFromSaleOfIntangibleAssets`	$10.00M	USD	Annual
Proceeds from disposal of land use right	`ProceedsFromDisposalOfLandUseRights`	$3.89M	USD	Annual
Proceeds from disposal of land use right	`ProceedsFromDisposalOfLandUseRights`	-	USD	Annual
Proceeds from disposal of land use right	`ProceedsFromDisposalOfLandUseRights`	-	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$249.96M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$420.02M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-10.78M	USD	Annual
Proceeds from exercises of stock options	`ProceedsFromStockOptionsExercised`	$5.87M	USD	Annual
Proceeds from exercises of stock options	`ProceedsFromStockOptionsExercised`	$7.42M	USD	Annual
Proceeds from exercises of stock options	`ProceedsFromStockOptionsExercised`	$2.37M	USD	Annual
Proceeds from issuance of ordinary shares upon public offerings	`ProceedsFromIssuanceInitialPublicOffering`	-	USD	Annual
Proceeds from issuance of ordinary shares upon public offerings	`ProceedsFromIssuanceInitialPublicOffering`	$818.88M	USD	Annual
Proceeds from issuance of ordinary shares upon public offerings	`ProceedsFromIssuanceInitialPublicOffering`	-	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	$1.84M	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	-	USD	Annual
Payment of public offering costs	`PaymentsOfStockIssuanceCosts`	-	USD	Annual
Taxes paid related to settlement of equity awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$7.60M	USD	Annual
Taxes paid related to settlement of equity awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$4.25M	USD	Annual
Taxes paid related to settlement of equity awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$8.80M	USD	Annual
Net cash (used in) provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-6.43M	USD	Annual
Net cash (used in) provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$-1.73M	USD	Annual
Net cash (used in) provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$820.20M	USD	Annual
Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$-2.62M	USD	Annual
Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$-6.27M	USD	Annual
Effect of foreign exchange rate changes on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$1.12M	USD	Annual
Net (decrease) increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$522.04M	USD	Annual
Net (decrease) increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$44.37M	USD	Annual
Net (decrease) increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-218.01M	USD	Annual
Cash, cash equivalents and restricted cash beginning of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$964.90M	USD	Point-in-time
Cash, cash equivalents and restricted cash beginning of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$442.86M	USD	Point-in-time
Cash, cash equivalents and restricted cash beginning of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$1.01B	USD	Point-in-time
Cash, cash equivalents and restricted cash beginning of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$791.26M	USD	Point-in-time
Cash, cash equivalents and restricted cash end of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$964.90M	USD	Point-in-time
Cash, cash equivalents and restricted cash end of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$442.86M	USD	Point-in-time
Cash, cash equivalents and restricted cash end of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$1.01B	USD	Point-in-time
Cash, cash equivalents and restricted cash end of the year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$791.26M	USD	Point-in-time
Payables for purchase of property and equipment	`NoncashOrPartNoncashAcquisitionFixedAssetsAcquired1`	$5.27M	USD	Annual
Payables for purchase of property and equipment	`NoncashOrPartNoncashAcquisitionFixedAssetsAcquired1`	$2.47M	USD	Annual
Payables for purchase of property and equipment	`NoncashOrPartNoncashAcquisitionFixedAssetsAcquired1`	$2.57M	USD	Annual
Payables for acquisition of intangible assets	`NonCashPayablesForIntangibleAssets`	$163.00K	USD	Annual
Payables for acquisition of intangible assets	`NonCashPayablesForIntangibleAssets`	$191.00K	USD	Annual
Payables for acquisition of intangible assets	`NonCashPayablesForIntangibleAssets`	$11.52M	USD	Annual
Payables for treasury stock	`NonCashPayablesForTreasuryStock`	$2.00K	USD	Annual
Payables for treasury stock	`NonCashPayablesForTreasuryStock`	-	USD	Annual
Payables for treasury stock	`NonCashPayablesForTreasuryStock`	$26.00K	USD	Annual
Right-of-use asset acquired under operating leases	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$3.67M	USD	Annual
Right-of-use asset acquired under operating leases	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$2.18M	USD	Annual
Right-of-use asset acquired under operating leases	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability`	$14.80M	USD	Annual
Receivables for disposal of property and equipment	`ReceivableRecognizedForDisposalOfPropertyAndEquipment`	$64.00K	USD	Annual
Receivables for disposal of property and equipment	`ReceivableRecognizedForDisposalOfPropertyAndEquipment`	-	USD	Annual
Receivables for disposal of property and equipment	`ReceivableRecognizedForDisposalOfPropertyAndEquipment`	-	USD	Annual
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$964.10M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$1.01B	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$790.15M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$1.11M	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$803.00K	USD	Point-in-time
Restricted cash, non-current	`RestrictedCashNoncurrent`	$803.00K	USD	Point-in-time
Total cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$964.90M	USD	Point-in-time
Total cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$442.86M	USD	Point-in-time
Total cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$1.01B	USD	Point-in-time
Total cash and cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$791.26M	USD	Point-in-time

Stockholders Equity 39 line items

Line Item	Tag	Value	Unit	Period
Issuance costs	`AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts`	$839.00K	USD	Annual
Beginning balance (in shares)	`CommonStockSharesOutstanding`	960.22M	shares	Point-in-time
Beginning balance (in shares)	`CommonStockSharesOutstanding`	972.24M	shares	Point-in-time
Beginning balance	`StockholdersEquity`	$1.38B	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$1.05B	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$796.12M	USD	Point-in-time
Beginning balance	`StockholdersEquity`	$1.17B	USD	Point-in-time
Beginning balance (in shares)	`TreasuryStockCommonShares`	4.91M	shares	Point-in-time
Beginning balance (in shares)	`TreasuryStockCommonShares`	2.24M	shares	Point-in-time
Issuance of ordinary shares upon vesting of restricted shares	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Issuance of ordinary shares upon vesting of restricted shares	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Issuance of ordinary shares upon vesting of restricted shares	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Exercise of shares options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	6.52M	shares	Annual
Exercise of share options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.55M	USD	Annual
Exercise of share options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$7.42M	USD	Annual
Exercise of share options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$5.87M	USD	Annual
Issuance of ordinary shares upon follow-on public offering, net of issuance cost	`StockIssuedDuringPeriodValueNewIssues`	$818.04M	USD	Annual
Issuance of ordinary shares in connection with collaboration and license arrangement (Note 16)	`StockIssuedDuringPeriodValueOther`	$62.25M	USD	Annual
Issuance cost adjustment for secondary listing	`IssuanceCostAdjustment`	$65.00K	USD	Annual
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$8.98M	USD	Annual
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$7.58M	USD	Annual
Receipt of shares netted to satisfy tax withholding obligations related to share-based compensation	`AdjustmentsRelatedToTaxWithholdingForShareBasedCompensation`	$4.28M	USD	Annual
Share-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$79.63M	USD	Annual
Share-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$61.30M	USD	Annual
Share-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$40.71M	USD	Annual
Net loss	`NetIncomeLoss`	$-334.62M	USD	Annual
Net loss	`NetIncomeLoss`	$-704.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-443.29M	USD	Annual
Foreign currency translation	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$11.94M	USD	Annual
Foreign currency translation	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$49.33M	USD	Annual
Foreign currency translation	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$-9.12M	USD	Annual
Ending balance (in shares)	`CommonStockSharesOutstanding`	960.22M	shares	Point-in-time
Ending balance (in shares)	`CommonStockSharesOutstanding`	972.24M	shares	Point-in-time
Ending balance	`StockholdersEquity`	$1.38B	USD	Point-in-time
Ending balance	`StockholdersEquity`	$1.05B	USD	Point-in-time
Ending balance	`StockholdersEquity`	$796.12M	USD	Point-in-time
Ending balance	`StockholdersEquity`	$1.17B	USD	Point-in-time
Ending balance (in shares)	`TreasuryStockCommonShares`	4.91M	shares	Point-in-time
Ending balance (in shares)	`TreasuryStockCommonShares`	2.24M	shares	Point-in-time

Comprehensive Income 12 line items

Line Item	Tag	Value	Unit	Period
Other comprehensive (loss) income, tax	`OtherComprehensiveIncomeLossTaxPortionAttributableToParent1`	-	USD	Annual
Other comprehensive (loss) income, tax	`OtherComprehensiveIncomeLossTaxPortionAttributableToParent1`	-	USD	Annual
Net loss	`NetIncomeLoss`	$-334.62M	USD	Annual
Net loss	`NetIncomeLoss`	$-704.47M	USD	Annual
Net loss	`NetIncomeLoss`	$-443.29M	USD	Annual
Other comprehensive (loss) income, tax	`OtherComprehensiveIncomeLossTaxPortionAttributableToParent1`	-	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$11.94M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$49.33M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent`	$-9.12M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-322.68M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-713.59M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-393.96M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.